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Stojmirović A, Yu YK. ITM Probe: analyzing information flow in protein networks. Bioinformatics. 2009;25(18):2447-9doi: 10.1093/bioinformatics/btp398.
Stojmirović, A., & Yu, Y. K. (2009). ITM Probe: analyzing information flow in protein networks. Bioinformatics (Oxford, England), 25(18), 2447-9. https://doi.org/10.1093/bioinformatics/btp398
Stojmirović, Aleksandar, and Yu, Yi-Kuo. "ITM Probe: analyzing information flow in protein networks." Bioinformatics (Oxford, England) vol. 25,18 (2009): 2447-9. doi: https://doi.org/10.1093/bioinformatics/btp398
Stojmirović A, Yu YK. ITM Probe: analyzing information flow in protein networks. Bioinformatics. 2009 Sep 15;25(18):2447-9. doi: 10.1093/bioinformatics/btp398. Epub 2009 Jun 27. PMID: 19561335; PMCID: PMC2735661.
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Bioinformatics. 2009 Sep 15;25(18):2447-9. doi: 10.1093/bioinformatics/btp398. Epub 2009 Jun 27.

ITM Probe: analyzing information flow in protein networks.

Bioinformatics (Oxford, England)

Aleksandar Stojmirović, Yi-Kuo Yu

Affiliations

  1. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

PMID: 19561335 PMCID: PMC2735661 DOI: 10.1093/bioinformatics/btp398

Abstract

SUMMARY: Founded upon diffusion with damping, ITM Probe is an application for modeling information flow in protein interaction networks without prior restriction to the sub-network of interest. Given a context consisting of desired origins and destinations of information, ITM Probe returns the set of most relevant proteins with weights and a graphical representation of the corresponding sub-network. With a click, the user may send the resulting protein list for enrichment analysis to facilitate hypothesis formation or confirmation.

AVAILABILITY: ITM Probe web service and documentation can be found at www.ncbi.nlm.nih.gov/CBBresearch/qmbp/mn/itm_probe.

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