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Bonzheim I, Geissinger E, Chuang WY, et al. Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas. J Hematop. 2008;1(1):11-21doi: 10.1007/s12308-008-0003-y.
Bonzheim, I., Geissinger, E., Chuang, W. Y., Roth, S., Ströbel, P., Marx, A., Reimer, P., Wilhelm, M., Puppe, B., Rosenwald, A., Müller-Hermelink, H. K., & Rüdiger, T. (2008). Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas. Journal of hematopathology, 1(1), 11-21. https://doi.org/10.1007/s12308-008-0003-y
Bonzheim, Irina, et al. "Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas." Journal of hematopathology vol. 1,1 (2008): 11-21. doi: https://doi.org/10.1007/s12308-008-0003-y
Bonzheim I, Geissinger E, Chuang WY, Roth S, Ströbel P, Marx A, Reimer P, Wilhelm M, Puppe B, Rosenwald A, Müller-Hermelink HK, Rüdiger T. Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas. J Hematop. 2008 Jul;1(1):11-21. doi: 10.1007/s12308-008-0003-y. Epub 2008 Apr 24. PMID: 19669200; PMCID: PMC2712330.
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J Hematop. 2008 Jul;1(1):11-21. doi: 10.1007/s12308-008-0003-y. Epub 2008 Apr 24.

Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas.

Journal of hematopathology

Irina Bonzheim, Eva Geissinger, Wen-Yu Chuang, Sabine Roth, Philipp Ströbel, Alexander Marx, Peter Reimer, Martin Wilhelm, Bernhard Puppe, Andreas Rosenwald, Hans Konrad Müller-Hermelink, Thomas Rüdiger

Affiliations

  1. Institute of Pathology, University of Würzburg, Josef Schneider Strasse 2, 97080, Würzburg, Germany, [email protected].

PMID: 19669200 PMCID: PMC2712330 DOI: 10.1007/s12308-008-0003-y

Abstract

Angioimmunoblastic T-cell lymphoma (AILT) represents a subset of T-cell lymphomas but resembles an autoimmune disease in many of its clinical aspects. Despite the phenotype of effector T-cells and high expression of FAS and CTLA-4 receptor molecules, tumor cells fail to undergo apoptosis. We investigated single nucleotide polymorphisms (SNPs) of the FAS and CTLA-4 genes in 94 peripheral T-cell lymphomas. Although allelic frequencies of some FAS SNPs were enriched in AILT cases, none of these occurred at a different frequency compared to healthy individuals. Therefore, SNPs in these genes are not associated with the apoptotic defect and autoimmune phenomena in AILT.

References

  1. Am J Surg Pathol. 1999 Jul;23(7):829-37 - PubMed
  2. J Immunol. 2000 Dec 1;165(11):6606-11 - PubMed
  3. Eur J Immunol. 1994 Dec;24(12):3057-62 - PubMed
  4. Genes Immun. 2005 Dec;6(8):699-706 - PubMed
  5. Science. 1995 Jun 2;268(5215):1347-9 - PubMed
  6. Cancer Genet Cytogenet. 2006 Mar;165(2):114-20 - PubMed
  7. J Immunol. 2000 May 15;164(10):5319-27 - PubMed
  8. Immunol Rev. 2005 Apr;204:102-15 - PubMed
  9. J Clin Invest. 1992 Aug;90(2):334-41 - PubMed
  10. J Exp Med. 1996 Mar 1;183(3):721-4 - PubMed
  11. Genes Immun. 2001 May;2(3):145-52 - PubMed
  12. Blood. 2001 Jul 1;98(1):194-200 - PubMed
  13. Blood. 2005 Aug 15;106(4):1501-2 - PubMed
  14. Mutat Res. 2001 Jul;488(3):211-31 - PubMed
  15. Am J Hematol. 2004 May;76(1):14-8 - PubMed
  16. Nat Rev Immunol. 2005 Nov;5(11):853-65 - PubMed
  17. Blood. 2002 Jan 15;99(2):627-33 - PubMed
  18. Blood. 1998 Nov 1;92(9):3018-24 - PubMed
  19. Semin Immunol. 1997 Apr;9(2):93-107 - PubMed
  20. Curr Opin Allergy Clin Immunol. 2004 Dec;4(6):497-503 - PubMed
  21. Cell. 1995 Jun 16;81(6):935-46 - PubMed
  22. Am J Surg Pathol. 2006 Apr;30(4):490-4 - PubMed
  23. Nature. 2003 May 29;423(6939):506-11 - PubMed
  24. J Mol Diagn. 2005 Oct;7(4):455-64 - PubMed
  25. J Pathol. 2006 Oct;210(2):172-80 - PubMed
  26. J Biol Chem. 2002 Nov 29;277(48):46478-86 - PubMed
  27. J Rheumatol. 2000 Oct;27(10):2397-405 - PubMed
  28. Blood. 2005 Mar 15;105(6):2443-8 - PubMed
  29. Hum Mol Genet. 1996 Jul;5(7):1075-80 - PubMed
  30. Blood. 1999 Nov 1;94(9):3067-76 - PubMed
  31. Am J Surg Pathol. 2005 Jul;29(7):903-11 - PubMed
  32. Immunol Rev. 2003 Jun;193:70-81 - PubMed
  33. Eur Neurol. 2004;52(1):12-7 - PubMed
  34. J Hum Genet. 2002;47(11):561-6 - PubMed
  35. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):628-32 - PubMed
  36. J Neuroimmunol. 2005 Apr;161(1-2):183-9 - PubMed
  37. Tissue Antigens. 1998 May;51(5):563-6 - PubMed
  38. Rheumatology (Oxford). 1999 Jun;38(6):516-20 - PubMed
  39. Nat Rev Immunol. 2002 Feb;2(2):116-26 - PubMed
  40. Clin Immunol. 1999 Oct;93(1):34-45 - PubMed
  41. Hum Genet. 2002 Oct;111(4-5):452-5 - PubMed
  42. Blood. 1998 May 15;91(10):3943-51 - PubMed
  43. Mod Pathol. 1998 Sep;11(9):864-9 - PubMed
  44. Ann Neurol. 2005 Oct;58(4):644-8 - PubMed
  45. Nat Genet. 1995 Nov;11(3):241-7 - PubMed
  46. Mol Cell Probes. 2006 Feb;20(1):21-6 - PubMed
  47. Bioinformatics. 2005 Jan 15;21(2):263-5 - PubMed
  48. Tissue Antigens. 1999 Jan;53(1):106-10 - PubMed
  49. Science. 1997 Feb 14;275(5302):960-3 - PubMed
  50. Arthritis Rheum. 2004 Jul;50(7):2211-5 - PubMed
  51. Int J Cancer. 2003 Jan 10;103(2):221-5 - PubMed
  52. Curr Opin Hematol. 1996 Jan;3(1):35-40 - PubMed
  53. Nat Rev Immunol. 2001 Dec;1(3):220-8 - PubMed
  54. Nat Immunol. 2004 Apr;5(4):380-7 - PubMed
  55. Am J Hum Genet. 1999 Apr;64(4):1002-14 - PubMed
  56. J Immunol. 2000 Aug 1;165(3):1352-6 - PubMed
  57. J Rheumatol. 2002 Jun;29(6):1183-8 - PubMed
  58. Semin Immunol. 1997 Feb;9(1):77-84 - PubMed
  59. J Immunol. 1999 Feb 1;162(3):1717-22 - PubMed
  60. Leuk Lymphoma. 2003 Aug;44(8):1317-23 - PubMed
  61. Am J Pathol. 1999 Jun;154(6):1785-91 - PubMed
  62. Br J Cancer. 2002 Jun 5;86(11):1776-85 - PubMed
  63. J Neuroimmunol. 2004 Jan;146(1-2):162-70 - PubMed
  64. Blood. 2001 Apr 15;97(8):2528 - PubMed
  65. Annu Rev Immunol. 2004;22:745-63 - PubMed
  66. Gastroenterology. 1997 Oct;113(4):1384-9 - PubMed
  67. Diabetologia. 2000 Jun;43(6):800-8 - PubMed
  68. Blood. 1997 Dec 1;90(11):4266-70 - PubMed

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