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Ji SH, Park JO, Lee J, et al. Three cases of synchronous solid tumor and multiple myeloma. Cancer Res Treat. 2004;36(5):338-40doi: 10.4143/crt.2004.36.5.338.
Ji, S. H., Park, J. O., Lee, J., Oh, M. J., Lim, D. H., Park, B. B., Park, K. W., Lee, S. H., Kim, K., Kim, W. S., Jung, C. W., Park, Y. S., Im, Y. H., Kang, W. K., Lee, M. H., & Park, K. (2004). Three cases of synchronous solid tumor and multiple myeloma. Cancer research and treatment, 36(5), 338-40. https://doi.org/10.4143/crt.2004.36.5.338
Ji, Sang Hoon, et al. "Three cases of synchronous solid tumor and multiple myeloma." Cancer research and treatment vol. 36,5 (2004): 338-40. doi: https://doi.org/10.4143/crt.2004.36.5.338
Ji SH, Park JO, Lee J, Oh MJ, Lim DH, Park BB, Park KW, Lee SH, Kim K, Kim WS, Jung CW, Park YS, Im YH, Kang WK, Lee MH, Park K. Three cases of synchronous solid tumor and multiple myeloma. Cancer Res Treat. 2004 Oct;36(5):338-40. doi: 10.4143/crt.2004.36.5.338. Epub 2004 Oct 31. PMID: 20368825; PMCID: PMC2843872.
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Cancer Res Treat. 2004 Oct;36(5):338-40. doi: 10.4143/crt.2004.36.5.338. Epub 2004 Oct 31.

Three cases of synchronous solid tumor and multiple myeloma.

Cancer research and treatment

Sang Hoon Ji, Joon Oh Park, Jeeyun Lee, Mi Jung Oh, Do Hyoung Lim, Byeong-Bae Park, Keun Woo Park, Se-Hoon Lee, Kihyun Kim, Won Seog Kim, Chul Won Jung, Young Suk Park, Young-Hyuck Im, Won Ki Kang, Mark H Lee, Keunchil Park

Affiliations

  1. Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

PMID: 20368825 PMCID: PMC2843872 DOI: 10.4143/crt.2004.36.5.338

Abstract

The association between a multiple myeloma and a secondary solid tumor is not well established. Some reports showed an increased risk of secondary solid neoplasms in multiple myeloma patients, but others have not. Three cases of the synchronous occurrence of multiple myelomas and solid tumors, namely, a small cell carcinoma of the lung, an adenocarcinoma of the colon and a squamous carcinoma of the pyriform sinus were experienced at our hospital. Therefore, herein is reported the clinical courses and treatment results. The stage of multiple myeloma was Durie-Salmon stage I in all of three cases; therefore, the solid tumors were treated as a primary target because the prognosis of early stage multiple myeloma is generally better than that of advanced solid tumor, while a smoldering or stage I myeloma do not need primary therapy until progression of the multiple myeloma. Two patients died of their solid tumors, but one patient is alive.

Keywords: Multiple myeloma; Second neoplasm; Synchronous neoplasm

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