Display options
Cite
Pontvianne F, Blevins T, Pikaard CS. Arabidopsis Histone Lysine Methyltransferases. Adv Bot Res. 2010;53:1-22doi: 10.1016/S0065-2296(10)53001-5.
Pontvianne, F., Blevins, T., & Pikaard, C. S. (2010). Arabidopsis Histone Lysine Methyltransferases. Advances in botanical research, 531-22. https://doi.org/10.1016/S0065-2296(10)53001-5
Pontvianne, Frédéric, et al. "Arabidopsis Histone Lysine Methyltransferases." Advances in botanical research vol. 53 (2010): 1-22. doi: https://doi.org/10.1016/S0065-2296(10)53001-5
Pontvianne F, Blevins T, Pikaard CS. Arabidopsis Histone Lysine Methyltransferases. Adv Bot Res. 2010 Jan 01;53:1-22. doi: 10.1016/S0065-2296(10)53001-5. PMID: 20703330; PMCID: PMC2918895.
Copy Download .nbib Format: NLM
Share it on

Adv Bot Res. 2010 Jan 01;53:1-22. doi: 10.1016/S0065-2296(10)53001-5.

Arabidopsis Histone Lysine Methyltransferases.

Advances in botanical research

Frédéric Pontvianne, Todd Blevins, Craig S Pikaard

Affiliations

  1. Department of Biology, Indiana University, 915 E. Third Street, Bloomington, IN, 47405, USA.

PMID: 20703330 PMCID: PMC2918895 DOI: 10.1016/S0065-2296(10)53001-5

Abstract

In eukaryotes, changes in chromatin structure regulate the access of gene regulatory sequences to the transcriptional machinery and play important roles in the repression of transposable elements, thereby protecting genome integrity. Chromatin dynamics and gene expression states are highly correlated, with DNA methylation and histone post-translational modifications playing important roles in the establishment or maintenance of chromatin states in plants. Histones can be covalently modified in a variety of ways, thereby affecting nucleosome spacing and/or higher-order nucleosome interactions directly or via the recruitment of histone-binding proteins. An extremely important group of chromatin modifying enzymes are the histone lysine methyltransferases (HKMTs). These enzymes are involved in the establishment and/or maintenance of euchromatic or heterochromatic states of active or transcriptionally repressed sequences, respectively. The vast majority of HKMTs possess a SET domain named for the three Drosophila proteins that are the founding members of the family: Suppressor of variegation, Enhancer of zeste and Trithorax. It is the SET domain that is responsible for HKMT enzymatic activity. Mutation of Arabidopsis HKMT genes can result in phenotypic abnormalities due to the improper regulation of important developmental genes. Here, we review the different classes of HKMTs present in the model plant Arabidopsis thaliana and discuss what is known about their biochemical and biological functions.

References

  1. Nature. 2004 Nov 18;432(7015):353-60 - PubMed
  2. Mol Cell Biol. 2008 Feb;28(4):1348-60 - PubMed
  3. Cell. 2007 Feb 23;128(4):693-705 - PubMed
  4. Genome Biol. 2009;10(6):R62 - PubMed
  5. EMBO J. 2007 Apr 4;26(7):1934-41 - PubMed
  6. Nucleic Acids Res. 2006;34(19):5461-70 - PubMed
  7. Plant Cell. 2006 May;18(5):1121-33 - PubMed
  8. Plant J. 2008 Dec;56(5):704-15 - PubMed
  9. Oncogene. 2004 Oct 7;23(46):7601-10 - PubMed
  10. Nucleic Acids Res. 2008 Jan;36(Database issue):D298-302 - PubMed
  11. Curr Opin Plant Biol. 2007 Dec;10(6):645-52 - PubMed
  12. Nature. 2007 Jul 19;448(7151):349-52 - PubMed
  13. Genes Dev. 2006 Dec 1;20(23):3249-54 - PubMed
  14. Dev Biol. 2007 Mar 1;303(1):259-69 - PubMed
  15. PLoS Biol. 2007 May;5(5):e129 - PubMed
  16. Cell. 2007 Jun 1;129(5):915-28 - PubMed
  17. Plant J. 2009 Apr;58(2):333-46 - PubMed
  18. Plant Cell. 2006 May;18(5):1166-76 - PubMed
  19. Biochim Biophys Acta. 2007 May-Jun;1769(5-6):316-29 - PubMed
  20. Nat Rev Mol Cell Biol. 2007 Jul;8(7):574-85 - PubMed
  21. Nature. 2003 Feb 6;421(6923):652-6 - PubMed
  22. Science. 2001 Aug 10;293(5532):1074-80 - PubMed
  23. Mol Cell. 1999 Apr;3(4):505-11 - PubMed
  24. Mol Cell. 2004 Apr 23;14(2):175-82 - PubMed
  25. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8823-7 - PubMed
  26. Nucleic Acids Res. 2001 Nov 1;29(21):4319-33 - PubMed
  27. EMBO J. 2005 Apr 6;24(7):1418-29 - PubMed
  28. EMBO J. 2005 Aug 3;24(15):2783-91 - PubMed
  29. J Biol Chem. 2006 Jul 14;281(28):19280-7 - PubMed
  30. EMBO J. 2006 Oct 4;25(19):4638-49 - PubMed
  31. Curr Biol. 2007 Feb 20;17(4):379-84 - PubMed
  32. Nat Cell Biol. 2005 Dec;7(12):1256-60 - PubMed
  33. Plant Mol Biol. 2008 Jan;66(1-2):47-59 - PubMed
  34. PLoS One. 2008 Sep 08;3(9):e3156 - PubMed
  35. Curr Biol. 2003 Dec 16;13(24):2212-7 - PubMed
  36. Gene. 2001 Jun 27;271(2):215-21 - PubMed
  37. Curr Opin Genet Dev. 2007 Dec;17(6):473-9 - PubMed
  38. Cell. 2008 May 2;133(3):523-36 - PubMed
  39. Nat Struct Mol Biol. 2006 Feb;13(2):140-6 - PubMed
  40. Nature. 2002 Apr 4;416(6880):556-60 - PubMed
  41. Development. 2008 Jun;135(11):1935-46 - PubMed
  42. Nat Struct Mol Biol. 2009 Jul;16(7):763-8 - PubMed
  43. Curr Opin Struct Biol. 2003 Dec;13(6):699-705 - PubMed
  44. Nucleic Acids Res. 2004 Dec 14;32(22):6511-8 - PubMed
  45. FEBS Lett. 2000 May 4;473(1):1-5 - PubMed
  46. Trends Plant Sci. 2005 Jan;10(1):30-5 - PubMed
  47. Cell. 2002 Oct 18;111(2):197-208 - PubMed
  48. PLoS Genet. 2008 Aug 15;4(8):e1000156 - PubMed
  49. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4186-91 - PubMed
  50. Plant J. 2003 Feb;33(3):471-80 - PubMed
  51. Curr Opin Cell Biol. 2002 Jun;14(3):286-98 - PubMed
  52. Cold Spring Harb Symp Quant Biol. 2004;69:145-53 - PubMed
  53. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14631-6 - PubMed
  54. Genes Dev. 2005 Jun 15;19(12):1444-54 - PubMed
  55. Curr Opin Struct Biol. 2006 Dec;16(6):753-60 - PubMed
  56. Cell. 2006 Feb 10;124(3):495-506 - PubMed
  57. Nature. 2006 Jul 6;442(7098):100-3 - PubMed
  58. EMBO Rep. 2007 Dec;8(12):1190-5 - PubMed
  59. Curr Biol. 2002 Oct 15;12(20):R694-5 - PubMed
  60. Development. 2009 Feb;136(4):509-23 - PubMed
  61. Curr Opin Struct Biol. 1997 Dec;7(6):798-803 - PubMed
  62. Plant Cell. 2000 Jul;12(7):1093-101 - PubMed
  63. Cell. 2002 Oct 4;111(1):91-103 - PubMed
  64. EMBO Rep. 2006 Sep;7(9):947-52 - PubMed
  65. Genes Dev. 2005 Jun 15;19(12):1455-65 - PubMed
  66. Int J Dev Biol. 2009;53(2-3):371-81 - PubMed
  67. Plant Cell. 2009 Jan;21(1):39-53 - PubMed
  68. Dev Biol. 2007 Jun 15;306(2):838-46 - PubMed
  69. Nat Struct Biol. 2002 Mar;9(3):217-24 - PubMed
  70. Nature. 2008 Mar 13;452(7184):215-9 - PubMed
  71. Curr Opin Plant Biol. 2004 Oct;7(5):521-6 - PubMed
  72. PLoS Genet. 2008 Nov;4(11):e1000280 - PubMed
  73. PLoS One. 2007 Nov 21;2(11):e1210 - PubMed
  74. Mol Cell Biol. 2004 Mar;24(6):2526-35 - PubMed
  75. Plant Physiol. 2003 Jun;132(2):907-25 - PubMed
  76. Science. 1998 Apr 17;280(5362):446-50 - PubMed
  77. Mol Cell Biol. 1993 Oct;13(10):6357-66 - PubMed
  78. Science. 2002 Sep 13;297(5588):1871-3 - PubMed
  79. Mutat Res. 2007 May 1;618(1-2):130-4 - PubMed
  80. Nature. 2000 Aug 10;406(6796):593-9 - PubMed
  81. Chromosoma. 2003 Aug;112(2):77-86 - PubMed
  82. EMBO J. 2002 Dec 16;21(24):6842-52 - PubMed
  83. Nucleic Acids Res. 2007;35(18):6290-6 - PubMed
  84. PLoS Genet. 2006 Jun 2;2(6):e83 - PubMed
  85. Plant Cell. 1999 Oct;11(10):1945-52 - PubMed
  86. Plant J. 2006 Aug;47(3):395-407 - PubMed
  87. Plant Cell. 2008 Mar;20(3):568-79 - PubMed
  88. Mol Cell. 2009 Feb 27;33(4):428-37 - PubMed
  89. Genome Res. 2003 Feb;13(2):137-44 - PubMed
  90. Plant J. 2004 Mar;37(5):707-19 - PubMed
  91. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):6049-54 - PubMed
  92. Mol Cell Biol. 2005 Dec;25(23):10507-15 - PubMed
  93. Curr Biol. 2002 Aug 20;12(16):1360-7 - PubMed
  94. Biochem Biophys Res Commun. 2008 Sep 5;373(4):659-64 - PubMed
  95. Nature. 1997 Sep 18;389(6648):251-60 - PubMed
  96. Cell. 2007 Nov 16;131(4):633-6 - PubMed
  97. Nature. 2009 Mar 19;458(7236):362-6 - PubMed
  98. Plant Cell. 2008 Mar;20(3):580-8 - PubMed
  99. Curr Biol. 2003 Apr 15;13(8):627-37 - PubMed
  100. J Biol Chem. 1999 Dec 17;274(51):36750-6 - PubMed
  101. Cell. 2006 Jul 14;126(1):79-92 - PubMed
  102. Genes Dev. 2007 Feb 1;21(3):267-77 - PubMed
  103. PLoS One. 2008;3(10):e3404 - PubMed
  104. Chromosoma. 2004 Mar;112(6):308-15 - PubMed
  105. Plant Physiol. 2009 Nov;151(3):1476-85 - PubMed
  106. Nature. 2006 Aug 17;442(7104):772-8 - PubMed
  107. Dev Biol. 2008 Mar 15;315(2):355-68 - PubMed
  108. Cell. 2006 Jul 14;126(1):93-106 - PubMed
  109. Mol Biol Evol. 2007 Feb;24(2):482-97 - PubMed

Publication Types

Grant support