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Cryst Growth Des. 2011 Jan 05;11(1):210-220. doi: 10.1021/cg101162a. Epub 2010 Nov 30.

Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be?.

Crystal growth & design

Doris E Braun, Panagiotis G Karamertzanis, Jean-Baptiste Arlin, Alastair J Florence, Volker Kahlenberg, Derek A Tocher, Ulrich J Griesser, Sarah L Price

PMID: 21218174 PMCID: PMC3015459 DOI: 10.1021/cg101162a

Abstract

An extensive experimental screen, coupled with a computational study, revealed seven new solid-state forms of β-resorcylic acid. The known, stable polymorph II° shows a reversible phase transformation to the new, kinetically stable, probably disordered high temperature form I. The study provides a consistent picture of the solid-state of β-resorcylic acid.

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