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Showing 1 to 12 of 156 entries
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Nanoparticle uptake by the oral route: Fulfilling its potential?.

Drug discovery today. Technologies

Florence AT.
PMID: 24981758
Drug Discov Today Technol. 2005;2(1):75-81. doi: 10.1016/j.ddtec.2005.05.019.

The absorption of nanoparticles from the gastrointestinal tract is discussed first from a recent historical perspective, emphasising the crucial parameters that influence uptake, such as particle diameter, the nature of the particle and any surface modification with ligands designed...

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Florence AT. Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug Discov Today Technol. 2005;2(1):75-81doi: 10.1016/j.ddtec.2005.05.019.
Florence, A. T. (2005). Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug discovery today. Technologies, 2(1), 75-81. https://doi.org/10.1016/j.ddtec.2005.05.019
Florence, Alexander T. "Nanoparticle uptake by the oral route: Fulfilling its potential?." Drug discovery today. Technologies vol. 2,1 (2005): 75-81. doi: https://doi.org/10.1016/j.ddtec.2005.05.019
Florence AT. Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug Discov Today Technol. 2005;2(1):75-81. doi: 10.1016/j.ddtec.2005.05.019. PMID: 24981758.
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Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones.

Angewandte Chemie (International ed. in English)

Paterson I, Florence GJ, Gerlach K, Scott JP.
PMID: 10649416
Angew Chem Int Ed Engl. 2000 Jan;39(2):377-380. doi: 10.1002/(sici)1521-3773(20000117)39:2<377::aid-anie377>3.0.co;2-e.

With a similar mechanism of action to taxol, the title compound 1 is a particularly promising candidate for development in cancer chemotherapy. This efficient synthesis, based on stereocontrolled aldol reactions, should help to overcome the scarce natural supply of...

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Paterson I, Florence GJ, Gerlach K, et al. Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones. Angew Chem Int Ed Engl. 2000;39(2):377-380doi: 10.1002/(sici)1521-3773(20000117)39:2<377::aid-anie377>3.0.co;2-e.
Paterson, I., Florence, G. J., Gerlach, K., & Scott, J. P. (2000). Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones. Angewandte Chemie (International ed. in English), 39(2), 377-380. https://doi.org/10.1002/(sici)1521-3773(20000117)39:2<377::aid-anie377>3.0.co;2-e
Paterson, et al. "Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones." Angewandte Chemie (International ed. in English) vol. 39,2 (2000): 377-380. doi: https://doi.org/10.1002/(sici)1521-3773(20000117)39:2<377::aid-anie377>3.0.co;2-e
Paterson I, Florence GJ, Gerlach K, Scott JP. Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones. Angew Chem Int Ed Engl. 2000 Jan;39(2):377-380. doi: 10.1002/(sici)1521-3773(20000117)39:2<377::aid-anie377>3.0.co;2-e. PMID: 10649416.
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Effects of Misoprostol on Bone Resorption and Formation in Organ Culture.

American journal of therapeutics

Raisz LG, Woodiel FN.
PMID: 11859384
Am J Ther. 1996 Feb;3(2):134-138. doi: 10.1097/00045391-199602000-00007.

Prostaglandins are potent stimulators of bone resorption and formation. Because misoprostol is an analog of prostaglandin E(1) (PGE(1)), we have examined its effects on resorption and formation in organ culture. The results were compared with PGE(2) which can stimulate...

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Raisz LG, Woodiel FN. Effects of Misoprostol on Bone Resorption and Formation in Organ Culture. Am J Ther. 1996;3(2):134-138doi: 10.1097/00045391-199602000-00007.
Raisz, L. G., & Woodiel, F. N. (1996). Effects of Misoprostol on Bone Resorption and Formation in Organ Culture. American journal of therapeutics, 3(2), 134-138. https://doi.org/10.1097/00045391-199602000-00007
Raisz, Lawrence G., and Woodiel, Florence N.. "Effects of Misoprostol on Bone Resorption and Formation in Organ Culture." American journal of therapeutics vol. 3,2 (1996): 134-138. doi: https://doi.org/10.1097/00045391-199602000-00007
Raisz LG, Woodiel FN. Effects of Misoprostol on Bone Resorption and Formation in Organ Culture. Am J Ther. 1996 Feb;3(2):134-138. doi: 10.1097/00045391-199602000-00007. PMID: 11859384.
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Toward the computational design of diastereomeric resolving agents: an experimental and computational study of 1-phenylethylammonium-2-phenylacetate derivatives.

The journal of physical chemistry. B

Karamertzanis PG, Anandamanoharan PR, Fernandes P, Cains PW, Vickers M, Tocher DA, Florence AJ, Price SL.
PMID: 17441754
J Phys Chem B. 2007 May 17;111(19):5326-36. doi: 10.1021/jp068530q. Epub 2007 Apr 19.

The crystal structures, including two new polymorphs, of three diastereomerically related salt pairs formed by (R)-1-phenylethylammonium (1) with (S&R)-2-phenylpropanoate (2), (S&R)-2-phenylbutyrate (3), and (S&R)-mandelate (4) ions were characterized by low-temperature single crystal or powder X-ray diffraction. Thermal, solubility, and...

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Karamertzanis PG, Anandamanoharan PR, Fernandes P, et al. Toward the computational design of diastereomeric resolving agents: an experimental and computational study of 1-phenylethylammonium-2-phenylacetate derivatives. J Phys Chem B. 2007;111(19):5326-36doi: 10.1021/jp068530q.
Karamertzanis, P. G., Anandamanoharan, P. R., Fernandes, P., Cains, P. W., Vickers, M., Tocher, D. A., Florence, A. J., & Price, S. L. (2007). Toward the computational design of diastereomeric resolving agents: an experimental and computational study of 1-phenylethylammonium-2-phenylacetate derivatives. The journal of physical chemistry. B, 111(19), 5326-36. https://doi.org/10.1021/jp068530q
Karamertzanis, Panagiotis G, et al. "Toward the computational design of diastereomeric resolving agents: an experimental and computational study of 1-phenylethylammonium-2-phenylacetate derivatives." The journal of physical chemistry. B vol. 111,19 (2007): 5326-36. doi: https://doi.org/10.1021/jp068530q
Karamertzanis PG, Anandamanoharan PR, Fernandes P, Cains PW, Vickers M, Tocher DA, Florence AJ, Price SL. Toward the computational design of diastereomeric resolving agents: an experimental and computational study of 1-phenylethylammonium-2-phenylacetate derivatives. J Phys Chem B. 2007 May 17;111(19):5326-36. doi: 10.1021/jp068530q. Epub 2007 Apr 19. PMID: 17441754.
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Coherent optical correlator using a deformable mirror device spatial light modulator in the Fourier plane.

Applied optics

Florence JM, Gale RO.
PMID: 20531713
Appl Opt. 1988 Jun 01;27(11):2091-3. doi: 10.1364/AO.27.002091.

No abstract available.

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Florence JM, Gale RO. Coherent optical correlator using a deformable mirror device spatial light modulator in the Fourier plane. Appl Opt. 1988;27(11):2091-3doi: 10.1364/AO.27.002091.
Florence, J. M., & Gale, R. O. (1988). Coherent optical correlator using a deformable mirror device spatial light modulator in the Fourier plane. Applied optics, 27(11), 2091-3. https://doi.org/10.1364/AO.27.002091
Florence, J M, and Gale, R O. "Coherent optical correlator using a deformable mirror device spatial light modulator in the Fourier plane." Applied optics vol. 27,11 (1988): 2091-3. doi: https://doi.org/10.1364/AO.27.002091
Florence JM, Gale RO. Coherent optical correlator using a deformable mirror device spatial light modulator in the Fourier plane. Appl Opt. 1988 Jun 01;27(11):2091-3. doi: 10.1364/AO.27.002091. PMID: 20531713.
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Health care models guiding mental health policy in Kenya 1965 - 1997.

International journal of mental health systems

Muga FA, Jenkins R.
PMID: 20426855
Int J Ment Health Syst. 2010 Apr 28;4(1):9. doi: 10.1186/1752-4458-4-9.

BACKGROUND: Mental health policy is needed to set the strategy and direction for the provision of mental health services in a country. Policy formulation does not occur in a vacuum, however, but is influenced by local and international factors...

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Muga FA, Jenkins R. Health care models guiding mental health policy in Kenya 1965 - 1997. Int J Ment Health Syst. 2010;4(1):9doi: 10.1186/1752-4458-4-9.
Muga, F. A., & Jenkins, R. (2010). Health care models guiding mental health policy in Kenya 1965 - 1997. International journal of mental health systems, 4(1), 9. https://doi.org/10.1186/1752-4458-4-9
Muga, Florence A, and Jenkins, Rachel. "Health care models guiding mental health policy in Kenya 1965 - 1997." International journal of mental health systems vol. 4,1 (2010): 9. doi: https://doi.org/10.1186/1752-4458-4-9
Muga FA, Jenkins R. Health care models guiding mental health policy in Kenya 1965 - 1997. Int J Ment Health Syst. 2010 Apr 28;4(1):9. doi: 10.1186/1752-4458-4-9. PMID: 20426855; PMCID: PMC2872652.
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Neglected diseases, neglected technologies, neglected patients?.

International journal of pharmaceutics

Florence AT.
PMID: 18191925
Int J Pharm. 2008 Feb 28;350(1):1-2. doi: 10.1016/j.ijpharm.2007.11.028. Epub 2007 Nov 22.

No abstract available.

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Florence AT. Neglected diseases, neglected technologies, neglected patients?. Int J Pharm. 2007;350(1):1-2doi: 10.1016/j.ijpharm.2007.11.028.
Florence, A. T. (2008). Neglected diseases, neglected technologies, neglected patients?. International journal of pharmaceutics, 350(1), 1-2. https://doi.org/10.1016/j.ijpharm.2007.11.028
Florence, Alexander T. "Neglected diseases, neglected technologies, neglected patients?." International journal of pharmaceutics vol. 350,1 (2008): 1-2. doi: https://doi.org/10.1016/j.ijpharm.2007.11.028
Florence AT. Neglected diseases, neglected technologies, neglected patients?. Int J Pharm. 2008 Feb 28;350(1):1-2. doi: 10.1016/j.ijpharm.2007.11.028. Epub 2007 Nov 22. PMID: 18191925.
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Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be?.

Crystal growth & design

Braun DE, Karamertzanis PG, Arlin JB, Florence AJ, Kahlenberg V, Tocher DA, Griesser UJ, Price SL.
PMID: 21218174
Cryst Growth Des. 2011 Jan 05;11(1):210-220. doi: 10.1021/cg101162a. Epub 2010 Nov 30.

An extensive experimental screen, coupled with a computational study, revealed seven new solid-state forms of β-resorcylic acid. The known, stable polymorph II° shows a reversible phase transformation to the new, kinetically stable, probably disordered high temperature form I. The...

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Braun DE, Karamertzanis PG, Arlin JB, et al. Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be?. Cryst Growth Des. 2010;11(1):210-220doi: 10.1021/cg101162a.
Braun, D. E., Karamertzanis, P. G., Arlin, J. B., Florence, A. J., Kahlenberg, V., Tocher, D. A., Griesser, U. J., & Price, S. L. (2011). Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be?. Crystal growth & design, 11(1), 210-220. https://doi.org/10.1021/cg101162a
Braun, Doris E, et al. "Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be?." Crystal growth & design vol. 11,1 (2011): 210-220. doi: https://doi.org/10.1021/cg101162a
Braun DE, Karamertzanis PG, Arlin JB, Florence AJ, Kahlenberg V, Tocher DA, Griesser UJ, Price SL. Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be?. Cryst Growth Des. 2011 Jan 05;11(1):210-220. doi: 10.1021/cg101162a. Epub 2010 Nov 30. PMID: 21218174; PMCID: PMC3015459.
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Personalised medicines.

International journal of pharmaceutics

Lee VH, Florence AT.
PMID: 21439365
Int J Pharm. 2011 Aug 30;415(1):1. doi: 10.1016/j.ijpharm.2011.03.035. Epub 2011 Mar 23.

No abstract available.

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Lee VH, Florence AT. Personalised medicines. Int J Pharm. 2011;415(1):1doi: 10.1016/j.ijpharm.2011.03.035.
Lee, V. H., & Florence, A. T. (2011). Personalised medicines. International journal of pharmaceutics, 415(1), 1. https://doi.org/10.1016/j.ijpharm.2011.03.035
Lee, Vincent H L, and Florence, Alexander T. "Personalised medicines." International journal of pharmaceutics vol. 415,1 (2011): 1. doi: https://doi.org/10.1016/j.ijpharm.2011.03.035
Lee VH, Florence AT. Personalised medicines. Int J Pharm. 2011 Aug 30;415(1):1. doi: 10.1016/j.ijpharm.2011.03.035. Epub 2011 Mar 23. PMID: 21439365.
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Application of emulsion theory to complex and real systems.

International journal of cosmetic science

Eccleston GM, Florence AT.
PMID: 19460027
Int J Cosmet Sci. 1985 Oct;7(5):195-212. doi: 10.1111/j.1467-2494.1985.tb00414.x.

Synopsis Theories of emulsion stability are discussed in relation to dilute, concentrated and semisolid emulsions. It is shown that whilst a unified theory cannot be applied quantitatively to emulsion systems, a better understanding of the various mechanisms of stabilization...

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Eccleston GM, Florence AT. Application of emulsion theory to complex and real systems. Int J Cosmet Sci. 1985;7(5):195-212doi: 10.1111/j.1467-2494.1985.tb00414.x.
Eccleston, G. M., & Florence, A. T. (1985). Application of emulsion theory to complex and real systems. International journal of cosmetic science, 7(5), 195-212. https://doi.org/10.1111/j.1467-2494.1985.tb00414.x
Eccleston, G M, and Florence, A T. "Application of emulsion theory to complex and real systems." International journal of cosmetic science vol. 7,5 (1985): 195-212. doi: https://doi.org/10.1111/j.1467-2494.1985.tb00414.x
Eccleston GM, Florence AT. Application of emulsion theory to complex and real systems. Int J Cosmet Sci. 1985 Oct;7(5):195-212. doi: 10.1111/j.1467-2494.1985.tb00414.x. PMID: 19460027.
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Cytenamide-formic acid (1/1).

Acta crystallographica. Section E, Structure reports online

Johnston A, Florence AJ, Miller GJ, Kennedy AR, Bedford CT.
PMID: 21203100
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 05;64:o1379-80. doi: 10.1107/S1600536808019181.

IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 5H-dibenzo[a,d]cyclo-hepta-triene-5-carboxamide-meth-anoic acid (1/1)], C(16)H(13)NO·CH(2)O(2), the cytenamide and solvent mol-ecules form a hydrogen-bonded R(2) (2)(8) dimer motif, which is further connected to form a centrosymmetric double-motif arrangement. The asymmetric unit...

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Johnston A, Florence AJ, Miller GJ, et al. Cytenamide-formic acid (1/1). Acta Crystallogr Sect E Struct Rep Online. 2008;64:o1379-80doi: 10.1107/S1600536808019181.
Johnston, A., Florence, A. J., Miller, G. J., Kennedy, A. R., & Bedford, C. T. (2008). Cytenamide-formic acid (1/1). Acta crystallographica. Section E, Structure reports online, 64o1379-80. https://doi.org/10.1107/S1600536808019181
Johnston, Andrea, et al. "Cytenamide-formic acid (1/1)." Acta crystallographica. Section E, Structure reports online vol. 64 (2008): o1379-80. doi: https://doi.org/10.1107/S1600536808019181
Johnston A, Florence AJ, Miller GJ, Kennedy AR, Bedford CT. Cytenamide-formic acid (1/1). Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 05;64:o1379-80. doi: 10.1107/S1600536808019181. PMID: 21203100; PMCID: PMC2962013.
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Tris-ACE-α-cyclodextrin tripods: chemistry and metal coordination behaviour.

Dalton transactions (Cambridge, England : 2003)

Guillaume P, Florence DC, Alain M.
PMID: 24081212
Dalton Trans. 2013 Dec 28;42(48):16806-17. doi: 10.1039/c3dt51811f. Epub 2013 Oct 01.

The synthesis of C3-symmetrical tris-(ACE)-(6,6'-bis-heterocyclyl)-α-cyclodextrins via"one pot" Staudinger-Aza-Wittig (SAW) reaction is described. The spectroscopic properties of their metal coordination compounds were analysed. The spontaneous formation of metallosupramolecular helicates generate strong exciton coupling features enlighten much information on the nature,...

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Guillaume P, Florence DC, Alain M. Tris-ACE-α-cyclodextrin tripods: chemistry and metal coordination behaviour. Dalton Trans. 2013;42(48):16806-17doi: 10.1039/c3dt51811f.
Guillaume, P., Florence, D. C., & Alain, M. (2013). Tris-ACE-α-cyclodextrin tripods: chemistry and metal coordination behaviour. Dalton transactions (Cambridge, England : 2003), 42(48), 16806-17. https://doi.org/10.1039/c3dt51811f
Guillaume, Poisson, et al. "Tris-ACE-α-cyclodextrin tripods: chemistry and metal coordination behaviour." Dalton transactions (Cambridge, England : 2003) vol. 42,48 (2013): 16806-17. doi: https://doi.org/10.1039/c3dt51811f
Guillaume P, Florence DC, Alain M. Tris-ACE-α-cyclodextrin tripods: chemistry and metal coordination behaviour. Dalton Trans. 2013 Dec 28;42(48):16806-17. doi: 10.1039/c3dt51811f. Epub 2013 Oct 01. PMID: 24081212.
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Showing 1 to 12 of 156 entries