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Rajan TV. H-2 Antigen variants in a cultured heterozygous mouse leukemia cell line : IV. Cell-Mediated cytolysis of wild type and variant cells. Immunogenetics. 1978;7(1):457-64doi: 10.1007/BF01844035.
Rajan, T. V. (1978). H-2 Antigen variants in a cultured heterozygous mouse leukemia cell line : IV. Cell-Mediated cytolysis of wild type and variant cells. Immunogenetics, 7(1), 457-64. https://doi.org/10.1007/BF01844035
Rajan, T V. "H-2 Antigen variants in a cultured heterozygous mouse leukemia cell line : IV. Cell-Mediated cytolysis of wild type and variant cells." Immunogenetics vol. 7,1 (1978): 457-64. doi: https://doi.org/10.1007/BF01844035
Rajan TV. H-2 Antigen variants in a cultured heterozygous mouse leukemia cell line : IV. Cell-Mediated cytolysis of wild type and variant cells. Immunogenetics. 1978 Dec;7(1):457-64. doi: 10.1007/BF01844035. PMID: 21302099.
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Immunogenetics. 1978 Dec;7(1):457-64. doi: 10.1007/BF01844035.

H-2 Antigen variants in a cultured heterozygous mouse leukemia cell line : IV. Cell-Mediated cytolysis of wild type and variant cells.

Immunogenetics

T V Rajan

Affiliations

  1. Departments of Pathology and Genetics, Albert Einstein College of Medicine, 10461, Bronx, New York.

PMID: 21302099 DOI: 10.1007/BF01844035

Abstract

H-2 antigen variants, derived from a heterozygous mouse Friend leukemia cell line by selection with anti-H-2 antisera and complement, were tested for susceptibility to cell-mediated cytolysis, using T-lymphocytes directed against individual H-2 antigens. The cytotoxic cells were generated in the BALB and B10 backgrounds by a combination of in vivo and in vitro immunizations. The phenotypes of the variants inferred from the patterns of resistance or susceptibility to CML were consistent with those presumed from earlier assays using antisera. The one exception was the variant cell line which was H-2D(d-) in assays using antisera, but was H-2D(d+) by CML.

References

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