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Showing 1 to 12 of 1434 entries
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Rising incidence of IDDM in Europe.

Diabetes care

Bingley PJ, Gale EA.
PMID: 2651055
Diabetes Care. 1989 Apr;12(4):289-95. doi: 10.2337/diacare.12.4.289.

A rising incidence of insulin-dependent diabetes mellitus (IDDM) has been reported in many northern European countries, with a rate equivalent to a doubling time of 20-30 yr in some. North American and Japanese studies report a similar trend, although...

Immunogenetics of graft-versus-host reactions to minor histocompatibility antigens.

Immunology today

Sprent J, Korngold R.
PMID: 25290241
Immunol Today. 1981 Oct;2(10):189-95. doi: 10.1016/0167-5699(81)90070-0.

No abstract available.

Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum Antigens.

Open forum infectious diseases

Arama C, Skinner J, Doumtabe D, Portugal S, Tran TM, Jain A, Traore B, Doumbo OK, Davies DH, Troye-Blomberg M, Dolo A, Felgner PL, Crompton PD.
PMID: 26361633
Open Forum Infect Dis. 2015 Aug 26;2(3):ofv118. doi: 10.1093/ofid/ofv118. eCollection 2015 Sep.

Background.  People of the Fulani ethnic group are more resistant to malaria compared with genetically distinct ethnic groups, such as the Dogon people, in West Africa, and studies suggest that this resistance is mediated by enhanced antibody responses to...

IMGT/StatClonotype for Pairwise Evaluation and Visualization of NGS IG and TR IMGT Clonotype (AA) Diversity or Expression from IMGT/HighV-QUEST.

Frontiers in immunology

Aouinti S, Giudicelli V, Duroux P, Malouche D, Kossida S, Lefranc MP.
PMID: 27667992
Front Immunol. 2016 Sep 09;7:339. doi: 10.3389/fimmu.2016.00339. eCollection 2016.

There is a huge need for standardized analysis and statistical procedures in order to compare the complex immune repertoires of antigen receptors immunoglobulins (IG) and T cell receptors (TR) obtained by next generation sequencing (NGS). NGS technologies generate millions...

Identification of glypican-3-derived long peptides activating both CD8.

Oncoimmunology

Sayem MA, Tomita Y, Yuno A, Hirayama M, Irie A, Tsukamoto H, Senju S, Yuba E, Yoshikawa T, Kono K, Nakatsura T, Nishimura Y.
PMID: 26942076
Oncoimmunology. 2015 Aug 31;5(1):e1062209. doi: 10.1080/2162402X.2015.1062209. eCollection 2016.

In a recent phase I clinical trial, a vaccine consisting of glypican-3 (GPC3)-derived CTL epitopes was found to be safe and induced measurable immune and clinical responses in patients with hepatocellular carcinoma (HCC). The aim of this study was...

Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen.

Frontiers in immunology

Hickey MJ, Valenzuela NM, Reed EF.
PMID: 26870045
Front Immunol. 2016 Feb 04;7:30. doi: 10.3389/fimmu.2016.00030. eCollection 2016.

Allorecognition is the activation of the adaptive immune system to foreign human leukocyte antigen (HLA) resulting in the generation of alloantibodies. Due to a high polymorphism, foreign HLA is recognized by the immune system following transplant, transfusion, or pregnancy...

Protective effects of melatonin on testis histology following acute torsion-detorsion in rats.

International journal of reproductive biomedicine

Mirhoseini M, Talebpour Amiri F, Karimpour Malekshah AA, Rezanejad Gatabi Z, Ghaffari E.
PMID: 28580446
Int J Reprod Biomed. 2017 Mar;15(3):141-146.

BACKGROUND: Testicular damage due to spermatic cord torsion may lead to infertility. It is probably because of changes in oxidative stress factors such as malondialdehyde.OBJECTIVE: To investigate the protective effect of melatonin (MLT), as an antioxidant, on testicular damage...

Allelic Polymorphism Determines Surface Expression or Intracellular Retention of the Human NK Cell Receptor KIR2DL5A (CD158f).

Frontiers in immunology

Cisneros E, Estefanía E, Vilches C.
PMID: 28144240
Front Immunol. 2017 Jan 17;7:698. doi: 10.3389/fimmu.2016.00698. eCollection 2016.

KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells to sense self-HLA. Unlike KIR2DL1-3, recognizing HLA-C allotypes through Ig-like domains of the D1-D2 type, KIR2DL5 shares a D0-D2 configuration...

Single-dose intravenous sodium valproate (Depakine) versus dexamethasone for the treatment of acute migraine headache: a double-blind randomized clinical trial.

Clinical and experimental emergency medicine

Karimi N, Tavakoli M, Charati JY, Shamsizade M.
PMID: 29026887
Clin Exp Emerg Med. 2017 Sep 30;4(3):138-145. doi: 10.15441/ceem.16.199. eCollection 2017 Sep.

OBJECTIVE: Migraine headache is a chronic and disabling condition in adults. Some studies have investigated the efficacy of sodium valproate in the treatment of acute migraine, but the effectiveness and tolerability of intravenous valproate as abortive therapy remains unclear....

Genetic variation in the extended major histocompatibility complex and susceptibility to childhood acute lymphoblastic leukemia: a review of the evidence.

Frontiers in oncology

Urayama KY, Thompson PD, Taylor M, Trachtenberg EA, Chokkalingam AP.
PMID: 24377085
Front Oncol. 2013 Dec 12;3:300. doi: 10.3389/fonc.2013.00300.

The enduring suspicion that infections and immunologic response may play a role in the etiology of childhood leukemia, particularly acute lymphoblastic leukemia (ALL), is now supported, albeit still indirectly, by numerous epidemiological studies. The cumulative evidence includes, for example,...

An old Twist in HLA-A: CDR3α Hook up at an R65-joint.

Frontiers in immunology

Murray JS.
PMID: 26074926
Front Immunol. 2015 May 27;6:268. doi: 10.3389/fimmu.2015.00268. eCollection 2015.

T-cell ontogeny optimizes the α/β T-cell receptor (TCR) repertoire for recognition of major histocompatibility complex (MHC) class-I/II genetic polymorphism, and co-evolution of TCR germline V-gene segments and the MHC must entail somatic diversity generated in the third complimentary determining...

Spondyloarthropathies: EULAR recommendations reflect advances in imaging.

Nature reviews. Rheumatology

Reveille JD.
PMID: 26055546
Nat Rev Rheumatol. 2015 Jul;11(7):388-9. doi: 10.1038/nrrheum.2015.80. Epub 2015 Jun 09.

No abstract available.

Showing 1 to 12 of 1434 entries