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Open Med Inform J. 2011;5:9-16. doi: 10.2174/1874431101105010009. Epub 2011 Apr 19.

GlycomicsDB - A Data Integration Platform for Glycans and their Strucutres.

The open medical informatics journal

Mahesh Visvanathan, Sasidhar R Siddam, In-Hee Lee, Gerald H Lushington, George R Bousfield

Affiliations

  1. Bioinformatics Core Facility, University of Kansas, Lawrence, KS 66047, USA.

PMID: 21603090 PMCID: PMC3098536 DOI: 10.2174/1874431101105010009

Abstract

Glycomics is a discipline of biology that deals with the structure and function of glycans (or carbohydrates). Analytical techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) are having a significant impact on the field of glycomics. However, effective progress in glycomics research requires collaboration between laboratories to share experimental data, structural information of glycans, and simulation results. Herein we report the development of a web-based data management system that can incorporate large volumes of data from disparate sources and organize them into a uniform format for users to store and access. This system enables participating laboratories to set up a shared data repository which members of interdisciplinary teams can access. The system is able to manage and share raw MS data and structural information of glycans.The database is available at http://www.glycomics.bcf.ku.edu.

Keywords: Functional glycomics; glycan structure.; mass spectrometry data; web-based data management system

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