Display options
Share it on

Int J Trichology. 2010 Jul;2(2):104-5. doi: 10.4103/0974-7753.77519.

Emerging issues with the current keratin-associated protein nomenclature.

International journal of trichology

Hua Gong, Huitong Zhou, Grant W McKenzie, Jonathan Gh Hickford, Zhidong Yu, Stefan Clerens, Jolon M Dyer, Jeffrey E Plowman

Affiliations

  1. Gene Marker Laboratory, Faculty of Agricultural Sciences, Lincoln University, NewZealand.

PMID: 21712897 PMCID: PMC3107952 DOI: 10.4103/0974-7753.77519

Abstract

Keratin associated proteins (KAPs) are a class of proteins that associate with keratin intermediate filament proteins through disulphide linkages to give fibres such as hair and wool their unique properties. Up to 90 proteins from some 25 families have been identified and this does not include polymorphic variants of individual proteins within these families. The existence of this diverse group of proteins has been known for some 75 years but, despite this, there is still no universally accepted nomenclature for them. This paper sets out the case for revising the current system to deal with this nomenclature issue.

Keywords: Hair; KAP; Keratin

References

  1. Anim Genet. 1994 Dec;25(6):407-15 - PubMed
  2. Biochem J. 1966 Mar;98(3):669-77 - PubMed
  3. Electron Microsc Rev. 1991;4(1):47-83 - PubMed
  4. J Invest Dermatol. 2005 Jun;124(6):1111-8 - PubMed
  5. J Biol Chem. 1948 Oct;176(1):337-65 - PubMed
  6. J Biol Chem. 2002 Nov 22;277(47):45493-501 - PubMed
  7. Mol Biol Rep. 2010 Oct;37(7):3377-80 - PubMed
  8. J Invest Dermatol. 2005 Jun;124(6):vii-ix - PubMed

Publication Types