80%) did not differ between groups (P = .435). Compliance in the therapy groups was high. All three programs proved feasible, suggesting they may be safely implemented for people with PD in community-based clinical practice." />
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McGinley JL, Martin C, Huxham FE, et al. Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease. Parkinsons Dis. 2011;2012:795294doi: 10.1155/2012/795294.
McGinley, J. L., Martin, C., Huxham, F. E., Menz, H. B., Danoudis, M., Murphy, A. T., Watts, J. J., Iansek, R., & Morris, M. E. (2012). Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease. Parkinson's disease, 2012795294. https://doi.org/10.1155/2012/795294
McGinley, Jennifer L, et al. "Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease." Parkinson's disease vol. 2012 (2012): 795294. doi: https://doi.org/10.1155/2012/795294
McGinley JL, Martin C, Huxham FE, Menz HB, Danoudis M, Murphy AT, Watts JJ, Iansek R, Morris ME. Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease. Parkinsons Dis. 2012;2012:795294. doi: 10.1155/2012/795294. Epub 2011 Dec 10. PMID: 22191076; PMCID: PMC3236432.
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Parkinsons Dis. 2012;2012:795294. doi: 10.1155/2012/795294. Epub 2011 Dec 10.

Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease.

Parkinson's disease

Jennifer L McGinley, Clarissa Martin, Frances E Huxham, Hylton B Menz, Mary Danoudis, Anna T Murphy, Jennifer J Watts, Robert Iansek, Meg E Morris

Affiliations

  1. Melbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, Australia.

PMID: 22191076 PMCID: PMC3236432 DOI: 10.1155/2012/795294

Abstract

Both efficacy and clinical feasibility deserve consideration in translation of research outcomes. This study evaluated the feasibility of rehabilitation programs within the context of a large randomized controlled trial of physical therapy. Ambulant participants with Parkinson's disease (PD) (n = 210) were randomized into three groups: (1) progressive strength training (PST); (2) movement strategy training (MST); or (3) control ("life skills"). PST and MST included fall prevention education. Feasibility was evaluated in terms of safety, retention, adherence, and compliance measures. Time to first fall during the intervention phase did not differ across groups, and adverse effects were minimal. Retention was high; only eight participants withdrew during or after the intervention phase. Strong adherence (attendance >80%) did not differ between groups (P = .435). Compliance in the therapy groups was high. All three programs proved feasible, suggesting they may be safely implemented for people with PD in community-based clinical practice.

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