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Drolet BA, Pope E, Juern AM, et al. Gastrointestinal bleeding in infantile hemangioma: a complication of segmental, rather than multifocal, infantile hemangiomas. J Pediatr. 2012;160(6):1021-6.e3doi: 10.1016/j.jpeds.2011.12.026.
Drolet, B. A., Pope, E., Juern, A. M., Sato, T., Howell, B., Puttgen, K. B., Lara-Corrales, I., Gilliam, A., Mancini, A., Powell, J., Siegel, D., Metry, D., Stevenson, D. A., Grimmer, J. F., & Frieden, I. J. (2012). Gastrointestinal bleeding in infantile hemangioma: a complication of segmental, rather than multifocal, infantile hemangiomas. The Journal of pediatrics, 160(6), 1021-6.e3. https://doi.org/10.1016/j.jpeds.2011.12.026
Drolet, Beth A, et al. "Gastrointestinal bleeding in infantile hemangioma: a complication of segmental, rather than multifocal, infantile hemangiomas." The Journal of pediatrics vol. 160,6 (2012): 1021-6.e3. doi: https://doi.org/10.1016/j.jpeds.2011.12.026
Drolet BA, Pope E, Juern AM, Sato T, Howell B, Puttgen KB, Lara-Corrales I, Gilliam A, Mancini A, Powell J, Siegel D, Metry D, Stevenson DA, Grimmer JF, Frieden IJ. Gastrointestinal bleeding in infantile hemangioma: a complication of segmental, rather than multifocal, infantile hemangiomas. J Pediatr. 2012 Jun;160(6):1021-6.e3. doi: 10.1016/j.jpeds.2011.12.026. Epub 2012 Jan 10. PMID: 22240112.
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J Pediatr. 2012 Jun;160(6):1021-6.e3. doi: 10.1016/j.jpeds.2011.12.026. Epub 2012 Jan 10.

Gastrointestinal bleeding in infantile hemangioma: a complication of segmental, rather than multifocal, infantile hemangiomas.

The Journal of pediatrics

Beth A Drolet, Elena Pope, Anna M Juern, Thomas Sato, Brandon Howell, Katherine Brown Puttgen, Irene Lara-Corrales, Amy Gilliam, Anthony Mancini, Julie Powell, Dawn Siegel, Denise Metry, David A Stevenson, Johannes F Grimmer, Ilona J Frieden

Affiliations

  1. Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA. [email protected]

PMID: 22240112 DOI: 10.1016/j.jpeds.2011.12.026

Abstract

OBJECTIVE: To highlight an association of facial segmental hemangiomas with gastrointestinal bleeding in infants with infantile hemangiomas.

STUDY DESIGN: We conducted a multicenter retrospective case series study.

RESULTS: Ten female patients met study inclusion criteria; 8 were Caucasian, 9 had a facial segmental hemangioma, and 9 cases met the diagnostic criteria for definitive posterior fossa malformations, hemangioma, arterial lesions, cardiac anomalies/coarctation of the aorta and eye abnormalities syndrome with abnormalities of the aorta and cerebral arteriopathy. Severe gastrointestinal bleeding requiring blood transfusion occurred in 9 cases, with age at presentation of gastrointestinal bleeding ranging from 8 days to 6 months. When detected, the location of the hemangioma in the small intestine was in the distribution of the superior mesenteric artery. More than one agent was required to control the gastrointestinal bleeding, including oral or intravenous steroids, vincristine, oral propranolol, interferon, and resection of the small intestine. All cases needed ongoing support care with red blood cell transfusions.

CONCLUSIONS: Gastrointestinal bleeding is a rare complication of true infantile hemangioma. The segmental pattern of the cutaneous hemangioma associated with gastrointestinal bleeding should suggest a segmental infantile hemangioma of the lower gastrointestinal tract.

Copyright © 2012 Mosby, Inc. All rights reserved.

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