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J Res Med Sci. 2011 Jul;16(7):945-50.

Study of relationship between clinical factors and velopharyngeal closure in cleft palate patients.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Qi Chen, Qian Zheng, Bing Shi, Heng Yin, Tian Meng, Guang-Ning Zheng

Affiliations

  1. Postgraduate, State Key Laboratory of Oral Disease, West China College of Stomatology, Sichuan University, Chengdu, PR China.

PMID: 22279464 PMCID: PMC3263109

Abstract

BACKGROUND: This study was carried out to analyze the relationship between clinical factors and velopharyngeal closure (VPC) in cleft palate patients.

METHODS: Chi-square test was used to compare the postoperative velopharyngeal closure rate. Logistic regression model was used to analyze independent variables associated with velopharyngeal closure.

RESULTS: Difference of postoperative VPC rate in different cleft types, operative ages and surgical techniques was significant (P=0.000). Results of logistic regression analysis suggested that when operative age was beyond deciduous dentition stage, or cleft palate type was complete, or just had undergone a simple palatoplasty without levator veli palatini retropositioning, patients would suffer a higher velopharyngeal insufficiency rate after primary palatal repair.

CONCLUSIONS: Cleft type, operative age and surgical technique were the contributing factors influencing VPC rate after primary palatal repair of cleft palate patients.

Keywords: Cleft palate; analysis; clinical factor; velopharyngeal closure

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