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Kovar H, Alonso J, Aman P, et al. The first European interdisciplinary ewing sarcoma research summit. Front Oncol. 2012;2:54doi: 10.3389/fonc.2012.00054.
Kovar, H., Alonso, J., Aman, P., Aryee, D. N., Ban, J., Burchill, S. A., Burdach, S., De Alava, E., Delattre, O., Dirksen, U., Fourtouna, A., Fulda, S., Helman, L. J., Herrero-Martin, D., Hogendoorn, P. C., Kontny, U., Lawlor, E. R., Lessnick, S. L., Llombart-Bosch, A., Metzler, M., Moriggl, R., Niedan, S., Potratz, J., Redini, F., Richter, G. H., Riedmann, L. T., Rossig, C., Schäfer, B. W., Schwentner, R., Scotlandi, K., Sorensen, P. H., Staege, M. S., Tirode, F., Toretsky, J., Ventura, S., Eggert, A., & Ladenstein, R. (2012). The first European interdisciplinary ewing sarcoma research summit. Frontiers in oncology, 254. https://doi.org/10.3389/fonc.2012.00054
Kovar, Heinrich, et al. "The first European interdisciplinary ewing sarcoma research summit." Frontiers in oncology vol. 2 (2012): 54. doi: https://doi.org/10.3389/fonc.2012.00054
Kovar H, Alonso J, Aman P, Aryee DN, Ban J, Burchill SA, Burdach S, De Alava E, Delattre O, Dirksen U, Fourtouna A, Fulda S, Helman LJ, Herrero-Martin D, Hogendoorn PC, Kontny U, Lawlor ER, Lessnick SL, Llombart-Bosch A, Metzler M, Moriggl R, Niedan S, Potratz J, Redini F, Richter GH, Riedmann LT, Rossig C, Schäfer BW, Schwentner R, Scotlandi K, Sorensen PH, Staege MS, Tirode F, Toretsky J, Ventura S, Eggert A, Ladenstein R. The first European interdisciplinary ewing sarcoma research summit. Front Oncol. 2012 May 29;2:54. doi: 10.3389/fonc.2012.00054. eCollection 2012. PMID: 22662320; PMCID: PMC3361960.
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Front Oncol. 2012 May 29;2:54. doi: 10.3389/fonc.2012.00054. eCollection 2012.

The first European interdisciplinary ewing sarcoma research summit.

Frontiers in oncology

Heinrich Kovar, Javier Alonso, Pierre Aman, Dave N T Aryee, Jozef Ban, Sue A Burchill, Stefan Burdach, Enrique De Alava, Olivier Delattre, Uta Dirksen, Argyro Fourtouna, Simone Fulda, Lee J Helman, David Herrero-Martin, Pancras C W Hogendoorn, Udo Kontny, Elizabeth R Lawlor, Stephen L Lessnick, Antonio Llombart-Bosch, Markus Metzler, Richard Moriggl, Stephan Niedan, Jenny Potratz, Françoise Redini, Günther H S Richter, Lucia T Riedmann, Claudia Rossig, Beat W Schäfer, Raphaela Schwentner, Katia Scotlandi, Poul H Sorensen, Martin S Staege, Franck Tirode, Jeffrey Toretsky, Selena Ventura, Angelika Eggert, Ruth Ladenstein

Affiliations

  1. Children's Cancer Research Institute, St. Anna Kinderkrebsforschung Vienna, Austria.

PMID: 22662320 PMCID: PMC3361960 DOI: 10.3389/fonc.2012.00054

Abstract

The European Network for Cancer Research in Children and Adolescents (ENCCA) provides an interaction platform for stakeholders in research and care of children with cancer. Among ENCCA objectives is the establishment of biology-based prioritization mechanisms for the selection of innovative targets, drugs, and prognostic markers for validation in clinical trials. Specifically for sarcomas, there is a burning need for novel treatment options, since current chemotherapeutic treatment protocols have met their limits. This is most obvious for metastatic Ewing sarcoma (ES), where long term survival rates are still below 20%. Despite significant progress in our understanding of ES biology, clinical translation of promising laboratory results has not yet taken place due to fragmentation of research and lack of an institutionalized discussion forum. To fill this gap, ENCCA assembled 30 European expert scientists and five North American opinion leaders in December 2011 to exchange thoughts and discuss the state of the art in ES research and latest results from the bench, and to propose biological studies and novel promising therapeutics for the upcoming European EWING2008 and EWING2012 clinical trials.

Keywords: Ewing sarcoma; animal models; biomarkers; drug screen; epigenetics; genomics; prognosis; sarcomagenesis

References

  1. J Clin Oncol. 2010 Apr 20;28(12):1982-8 - PubMed
  2. Oncogene. 2012 Mar 8;31(10):1287-98 - PubMed
  3. Nature. 2011 Jul 04;476(7360):293-7 - PubMed
  4. PLoS Med. 2007 Apr;4(4):e122 - PubMed
  5. Cancer Cell. 2009 May 5;15(5):402-15 - PubMed
  6. Cancer Res. 1990 Jan 1;50(1):38-43 - PubMed
  7. Br J Cancer. 2002 Jun 5;86(11):1763-9 - PubMed
  8. Genes Chromosomes Cancer. 2008 Mar;47(3):207-20 - PubMed
  9. Ann Oncol. 2012 Aug;23(8):2185-2190 - PubMed
  10. Br J Cancer. 2011 Mar 15;104(6):948-56 - PubMed
  11. Cancer. 1973 Apr;31(4):889-93 - PubMed
  12. J Biol Chem. 2012 Feb 10;287(7):4485-91 - PubMed
  13. Mol Cancer Res. 2012 Mar;10(3):336-46 - PubMed
  14. BMC Cancer. 2010 Mar 26;10:116 - PubMed
  15. Cancer Immunol Immunother. 2012 Jan;61(1):127-35 - PubMed
  16. Cancer Res. 2004 Nov 15;64(22):8349-56 - PubMed
  17. J Pathol. 2011 Nov;225(3):353-63 - PubMed
  18. Nat Genet. 2012 Feb 12;44(3):323-7 - PubMed
  19. Cancer Res. 2003 Mar 1;63(5):1122-9 - PubMed
  20. Cell Cycle. 2011 Oct 1;10(19):3397-408 - PubMed
  21. Pediatr Blood Cancer. 2009 Mar;52(3):324-7 - PubMed
  22. Acta Neuropathol. 2011 Dec;122(6):657-71 - PubMed
  23. Nature. 1992 Sep 10;359(6391):162-5 - PubMed
  24. J Pathol. 2012 Apr;226(5):796-805 - PubMed
  25. Cancer Res. 2010 Nov 1;70(21):8770-81 - PubMed
  26. Cancer Res. 2008 Sep 1;68(17):7100-9 - PubMed
  27. Br J Cancer. 2012 Mar 13;106(6):1123-33 - PubMed
  28. Cell Stem Cell. 2011 May 6;8(5):511-24 - PubMed
  29. Oncogene. 2011 Jun 16;30(24):2730-40 - PubMed
  30. J Natl Cancer Inst. 2011 Jun 22;103(12):962-78 - PubMed
  31. Nat Med. 2009 Jul;15(7):750-6 - PubMed
  32. Int J Cancer. 2012 Nov 1;131(9):2153-64 - PubMed
  33. Cancer Res. 2009 Mar 1;69(5):1776-81 - PubMed
  34. Cancer Res. 2010 Oct 1;70(19):7610-9 - PubMed
  35. Blood. 2011 Dec 1;118(23):6050-6 - PubMed
  36. J Clin Oncol. 2011 Dec 1;29(34):4581-3 - PubMed
  37. Trends Biotechnol. 2011 Nov;29(11):550-7 - PubMed
  38. BMC Cancer. 2009 Jan 14;9:17 - PubMed
  39. Mol Cancer Res. 2012 Jan;10(1):52-65 - PubMed
  40. Clin Cancer Res. 2009 Aug 1;15(15):4857-66 - PubMed
  41. Oncotarget. 2011 Dec;2(12):896-917 - PubMed
  42. Nature. 2010 Apr 1;464(7289):792-6 - PubMed
  43. Cancer Res. 2008 Nov 1;68(21):8968-75 - PubMed
  44. Oncogene. 2011 May 5;30(18):2173-80 - PubMed
  45. PLoS One. 2011;6(7):e22733 - PubMed
  46. Cell Death Differ. 2012 Mar;19(3):501-10 - PubMed
  47. J Clin Invest. 2010 Aug;120(8):2979-88 - PubMed
  48. Am J Pathol. 2007 Jun;170(6):1917-30 - PubMed

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