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Showing 1 to 12 of 85 entries
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Does the use of primary continuous positive airway pressure reduce the need for intubation and mechanical ventilation in infants ≤32 weeks' gestation?.

Paediatrics & child health

Yee WH, Scotland J, Pham Y, Finch R.
PMID: 23204903
Paediatr Child Health. 2011 Dec;16(10):633-7.

BACKGROUND: Ventilator-induced lung injury is a recognized risk factor for bronchopulmonary dysplasia.OBJECTIVE: To determine whether primary continuous positive airway pressure (CPAP), defined as CPAP without previous endotracheal intubation for any indication, can reduce the need for intubation and mechanical...

Value of immunohistochemical detection of noncollagenous proteins of bone for the diagnosis of bone tumours.

International journal of oncology

Serra M, Scotlandi K, Sollazzo M, Sarti M, Maurici D, Benini S, Picci P, Bertoni F, Baldini N.
PMID: 21541509
Int J Oncol. 1996 Aug;9(2):257-61.

The expression of osteonectin, osteopontin, bone sialoprotein, and osteocalcin was evaluated by immunohistochemistry in 57 cases of osteoid-forming and non-osteoid-forming bone tumours using specific polyclonal antibodies and the avidin-biotin peroxidase complex method. A positive immunostaining was found in all...

Educational barriers of nurses caring for sick and at-risk infants in India.

International nursing review

Campbell-Yeo M, Deorari A, McMillan DD, Singhal N, Vatsa M, Aylward D, Scotland J, Kumar P, Joshi M, Kalyan G, Dol J.
PMID: 25131708
Int Nurs Rev. 2014 Sep;61(3):398-405. doi: 10.1111/inr.12121. Epub 2014 Aug 08.

AIM: To gain ideas and information from healthcare providers to optimize the education and clinical practices of nurses caring for sick or at-risk newborns in India.BACKGROUND: Improving infant survival has been identified as a Millennium Development Goals; however, India...

The first European interdisciplinary ewing sarcoma research summit.

Frontiers in oncology

Kovar H, Alonso J, Aman P, Aryee DN, Ban J, Burchill SA, Burdach S, De Alava E, Delattre O, Dirksen U, Fourtouna A, Fulda S, Helman LJ, Herrero-Martin D, Hogendoorn PC, Kontny U, Lawlor ER, Lessnick SL, Llombart-Bosch A, Metzler M, Moriggl R, Niedan S, Potratz J, Redini F, Richter GH, Riedmann LT, Rossig C, Schäfer BW, Schwentner R, Scotlandi K, Sorensen PH, Staege MS, Tirode F, Toretsky J, Ventura S, Eggert A, Ladenstein R.
PMID: 22662320
Front Oncol. 2012 May 29;2:54. doi: 10.3389/fonc.2012.00054. eCollection 2012.

The European Network for Cancer Research in Children and Adolescents (ENCCA) provides an interaction platform for stakeholders in research and care of children with cancer. Among ENCCA objectives is the establishment of biology-based prioritization mechanisms for the selection of...

CD99: A Cell Surface Protein with an Oncojanus Role in Tumors.

Genes

Manara MC, Pasello M, Scotlandi K.
PMID: 29534016
Genes (Basel). 2018 Mar 13;9(3). doi: 10.3390/genes9030159.

The cell surface molecule CD99 has gained interest because of its involvement in regulating cell differentiation and adhesion/migration of immune and tumor cells. However, the molecule plays an intriguing and dual role in different cell types. In particular, it...

Correction: Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation.

PLoS genetics

Xia C, Amador C, Huffman J, Trochet H, Campbell A, Porteous D, Scotland G, Hastie ND, Hayward C, Vitart V, Navarro P, Haley CS.
PMID: 28196069
PLoS Genet. 2017 Feb 14;13(2):e1006608. doi: 10.1371/journal.pgen.1006608. eCollection 2017 Feb.

[This corrects the article DOI: 10.1371/journal.pgen.1005804.].

Tumoral immune-infiltrate (IF), PD-L1 expression and role of CD8/TIA-1 lymphocytes in localized osteosarcoma patients treated within protocol ISG-OS1.

Oncotarget

Palmerini E, Agostinelli C, Picci P, Pileri S, Marafioti T, Lollini PL, Scotlandi K, Longhi A, Benassi MS, Ferrari S.
PMID: 29340095
Oncotarget. 2017 Dec 04;8(67):111836-111846. doi: 10.18632/oncotarget.22912. eCollection 2017 Dec 19.

BACKGROUND: We hypothesized that immune-infiltrates were associated with superior survival, and examined a primary osteosarcoma tissue microarrays (TMAs) to test this hypothesis.METHODS: 129 patients (pts) with localized osteosarcoma treated within protocol ISG-OS1 were included in the study. Clinical characteristics,...

Correction: Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

Journal of medical Internet research

Midaglia L, Mulero P, Montalban X, Graves J, Hauser SL, Julian L, Baker M, Schadrack J, Gossens C, Scotland A, Lipsmeier F, van Beek J, Bernasconi C, Belachew S, Lindemann M.
PMID: 31596725
J Med Internet Res. 2019 Oct 08;21(10):e16287. doi: 10.2196/16287.

[This corrects the article DOI: 10.2196/14863.].

Consensus Statement on Urinary Stone Treatment During A Pandemic: A Delphi Process from the Endourological Society TOWER Research Initiative.

Journal of endourology

Scotland K, Tailly T, Chew BH, Bhojani N, Smith RD.
PMID: 35019782
J Endourol. 2022 Jan 12; doi: 10.1089/end.2021.0477. Epub 2022 Jan 12.

INTRODUCTION: The COVID-19 pandemic has had a significant impact on the care of patients with urolithiasis. Recommendations and prioritization of endourologic surgical procedures vary among regions and a comprehensive overall international directive is needed. We used the Delphi method...

Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury.

BMC nephrology

Jacobsen E, Sawhney S, Brazzelli M, Aucott L, Scotland G, Aceves-Martins M, Robertson C, Imamura M, Poobalan A, Manson P, Kaye C, Boyers D.
PMID: 34852765
BMC Nephrol. 2021 Dec 01;22(1):399. doi: 10.1186/s12882-021-02610-9.

BACKGROUND: Early and accurate acute kidney injury (AKI) detection may improve patient outcomes and reduce health service costs. This study evaluates the diagnostic accuracy and cost-effectiveness of NephroCheck and NGAL (urine and plasma) biomarker tests used alongside standard care,...

Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma.

Nature communications

Zoumpoulidou G, Alvarez-Mendoza C, Mancusi C, Ahmed RM, Denman M, Steele CD, Tarabichi M, Roy E, Davies LR, Manji J, Cristalli C, Scotlandi K, Pillay N, Strauss SJ, Mittnacht S.
PMID: 34862364
Nat Commun. 2021 Dec 03;12(1):7064. doi: 10.1038/s41467-021-27291-8.

Loss-of-function mutations in the RB1 tumour suppressor are key drivers in cancer, including osteosarcoma. RB1 loss-of-function compromises genome-maintenance and hence could yield vulnerability to therapeutics targeting such processes. Here we demonstrate selective hypersensitivity to clinically-approved inhibitors of Poly-ADP-Polymerase1,2 inhibitors...

Targeting CD99 Compromises the Oncogenic Effects of the Chimera EWS-FLI1 by Inducing Reexpression of Zyxin and Inhibition of GLI1 Activity.

Molecular cancer therapeutics

Balestra T, Manara MC, Laginestra MA, Pasello M, De Feo A, Bassi C, Guerzoni C, Landuzzi L, Lollini PL, Donati DM, Negrini M, Magnani M, Scotlandi K.
PMID: 34667115
Mol Cancer Ther. 2021 Oct 19; doi: 10.1158/1535-7163.MCT-21-0189. Epub 2021 Oct 19.

Ewing sarcoma, a highly aggressive pediatric tumor, is driven by EWS-FLI1, an oncogenic transcription factor that remodels the tumor genetic landscape. Epigenetic mechanisms play a pivotal role in Ewing sarcoma pathogenesis, and the therapeutic value of compounds targeting epigenetic...

Showing 1 to 12 of 85 entries