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Ann Rehabil Med. 2012 Aug;36(4):578-83. doi: 10.5535/arm.2012.36.4.578. Epub 2012 Aug 27.

Rehabilitation for ataxia following chemotherapy for burkitt lymphoma involving the rectum.

Annals of rehabilitation medicine

Hyoung Seop Kim, Chul Oh Jung, Ha Ra Jeon, Lee Ho Sung

Affiliations

  1. Department of Physical Medicine and Rehabilitation, National Health Insurance Corporation Ilsan Hospital, Korea.

PMID: 22977788 PMCID: PMC3438429 DOI: 10.5535/arm.2012.36.4.578

Abstract

Burkitt lymphoma is a type of B-cell lymphoma that occurs mostly in children, and rarely in adults. The sporadic type is known to occur mostly at the ileum and cecum. Cytarabine, which is used for central nervous system prophylaxis during chemotherapy for Burkitt lymphoma, has known neurotoxicity, and its side effects include motor ataxia due to cerebellar injury, ataxic dysarthria, dysfunction of ocular movement, confusion, somnolence and lethargy. This case report is about a patient diagnosed with Burkitt lymphoma who manifested motor ataxia after chemotherapy that included cytarabine.

Keywords: Ataxia; Cerebellar toxicity; Cytarabine

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