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Mizunoya W, Ohnuki K, Baba K, et al. Effect of dietary fat type on anxiety-like and depression-like behavior in mice. Springerplus. 2013;2(1):165doi: 10.1186/2193-1801-2-165.
Mizunoya, W., Ohnuki, K., Baba, K., Miyahara, H., Shimizu, N., Tabata, K., Kino, T., Sato, Y., Tatsumi, R., & Ikeuchi, Y. (2013). Effect of dietary fat type on anxiety-like and depression-like behavior in mice. SpringerPlus, 2(1), 165. https://doi.org/10.1186/2193-1801-2-165
Mizunoya, Wataru, et al. "Effect of dietary fat type on anxiety-like and depression-like behavior in mice." SpringerPlus vol. 2,1 (2013): 165. doi: https://doi.org/10.1186/2193-1801-2-165
Mizunoya W, Ohnuki K, Baba K, Miyahara H, Shimizu N, Tabata K, Kino T, Sato Y, Tatsumi R, Ikeuchi Y. Effect of dietary fat type on anxiety-like and depression-like behavior in mice. Springerplus. 2013 Apr 16;2(1):165. doi: 10.1186/2193-1801-2-165. Print 2013 Dec. PMID: 23667814; PMCID: PMC3647083.
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Springerplus. 2013 Apr 16;2(1):165. doi: 10.1186/2193-1801-2-165. Print 2013 Dec.

Effect of dietary fat type on anxiety-like and depression-like behavior in mice.

SpringerPlus

Wataru Mizunoya, Koichiro Ohnuki, Kento Baba, Hideo Miyahara, Naomi Shimizu, Kuniko Tabata, Takako Kino, Yusuke Sato, Ryuichi Tatsumi, Yoshihide Ikeuchi

Affiliations

  1. Department of Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6-10-1 Hakozaki, Fukuoka, Higashi-ku, 812-8581 Japan.

PMID: 23667814 PMCID: PMC3647083 DOI: 10.1186/2193-1801-2-165

Abstract

Dietary fat plays an important role in higher brain functions. We aimed to assess the short and long term intake of three different types of dietary fat (soybean oil, lard, and fish oil) on anxiety-like and depression-like behavior in mice. For the short term intake assessment, a behavioral test battery for anxiety and depression was carried out for a 3-day feeding period. For the long term intake assessment, a behavioral test battery began after the 4-week feeding period. During the short term intake, the time spent in the open arms of the elevated plus-maze was the longest in the fish oil fed group, followed by the soybean oil and lard-fed groups. The elevated plus-maze is a common animal model to assess anxiety, in which an increased time spent in the open arms indicates an anxiolytic effect. The difference between the fish oil-fed group and lard-fed group was statistically significant (p < 0.01), but there was no significant difference between the soybean oil-fed group and the other two groups. Similar results were observed after a 4-week feeding period. On the other hand, there was no significant difference among the three groups in behavior tests to evaluate depression. Thus, the dietary fat types appeared to influence anxiety but not depression in mice, both in short term (3 days) and long term (4 weeks) feeding.

Keywords: Anxiety; Depression; Fish oil; Lard; Soybean oil

References

  1. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8987-92 - PubMed
  2. Behav Brain Res. 1997 Apr;85(1):57-69 - PubMed
  3. Ann N Y Acad Sci. 2006 Nov;1086:144-59 - PubMed
  4. J Lipid Res. 1988 Aug;29(8):1013-21 - PubMed
  5. J Lipid Res. 2001 Jul;42(7):1160-8 - PubMed
  6. Nature. 1977 Apr 21;266(5604):730-2 - PubMed
  7. J Nutr. 1997 May;127(5 Suppl):838S-841S - PubMed
  8. Physiol Behav. 2004 Jun;81(4):605-13 - PubMed
  9. Arch Gen Psychiatry. 2002 Oct;59(10):913-9 - PubMed
  10. Nat Neurosci. 2011 Mar;14(3):345-50 - PubMed
  11. Physiol Behav. 1994 Sep;56(3):623-8 - PubMed
  12. Behav Brain Res. 1998 Nov;96(1-2):195-205 - PubMed
  13. Clin Exp Pharmacol Physiol. 2001 Apr;28(4):266-70 - PubMed
  14. J Nutr. 1998 Sep;128(9):1537-42 - PubMed
  15. Behav Brain Res. 1997 Apr;85(1):27-35 - PubMed
  16. Biol Psychiatry. 2006 Mar 1;59(5):415-23 - PubMed
  17. Biochem J. 1983 May 1;211(2):507-9 - PubMed
  18. Neurosci Biobehav Rev. 1998;22(1):33-57 - PubMed
  19. Lancet. 1998 Apr 18;351(9110):1213 - PubMed
  20. Psychosom Med. 2007 Apr;69(3):217-24 - PubMed
  21. Cell. 2001 Nov 30;107(5):617-29 - PubMed
  22. Prostaglandins Leukot Essent Fatty Acids. 2007 Nov-Dec;77(5-6):269-77 - PubMed
  23. Behav Brain Res. 2008 Nov 21;193(2):277-88 - PubMed
  24. J Nutr. 1989 Dec;119(12):1880-92 - PubMed
  25. J Clin Psychiatry. 2011 Dec;72(12):1577-84 - PubMed
  26. Science. 1992 Dec 18;258(5090):1946-9 - PubMed
  27. Psychopharmacology (Berl). 1985;85(3):367-70 - PubMed
  28. J Lipid Res. 1993 Feb;34(2):239-47 - PubMed
  29. J Lipid Res. 2000 Mar;41(3):473-80 - PubMed
  30. Neuroscience. 1999;93(1):237-41 - PubMed
  31. Brain Res. 2003 Feb 21;964(1):136-43 - PubMed
  32. J Membr Biol. 1993 Jan;131(1):35-42 - PubMed
  33. J Physiol Biochem. 2012 Dec;68(4):671-81 - PubMed
  34. Neuropsychopharmacology. 2003 Jun;28(6):1031-44 - PubMed
  35. Nature. 2006 Jun 1;441(7093):595-600 - PubMed
  36. Am J Psychiatry. 2004 Mar;161(3):567-9 - PubMed
  37. Eur J Pharmacol. 1978 Feb 15;47(4):379-91 - PubMed
  38. Physiol Behav. 1999 Dec 1-15;68(1-2):47-53 - PubMed
  39. Brain Res. 2007 May 30;1150:100-7 - PubMed
  40. Semin Psychiatry. 1971 Nov;3(4):435-48 - PubMed
  41. Proc Soc Exp Biol Med. 1986 May;182(1):127-31 - PubMed
  42. Life Sci. 1995;57(21):1935-47 - PubMed
  43. Psychopharmacology (Berl). 1993;111(3):323-31 - PubMed
  44. Psychopharmacology (Berl). 1994 Jan;113(3-4):543-6 - PubMed

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