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Khan S, Smulders YM, de Vries JI, et al. Life-threatening complications of hormonal contraceptives: a case history. Case Rep Obstet Gynecol. 2013;2013:186230doi: 10.1155/2013/186230.
Khan, S., Smulders, Y. M., de Vries, J. I., & Spoelstra-de Man, A. M. (2013). Life-threatening complications of hormonal contraceptives: a case history. Case reports in obstetrics and gynecology, 2013186230. https://doi.org/10.1155/2013/186230
Khan, Saheed, et al. "Life-threatening complications of hormonal contraceptives: a case history." Case reports in obstetrics and gynecology vol. 2013 (2013): 186230. doi: https://doi.org/10.1155/2013/186230
Khan S, Smulders YM, de Vries JI, Spoelstra-de Man AM. Life-threatening complications of hormonal contraceptives: a case history. Case Rep Obstet Gynecol. 2013;2013:186230. doi: 10.1155/2013/186230. Epub 2013 May 20. PMID: 23762682; PMCID: PMC3671505.
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Case Rep Obstet Gynecol. 2013;2013:186230. doi: 10.1155/2013/186230. Epub 2013 May 20.

Life-threatening complications of hormonal contraceptives: a case history.

Case reports in obstetrics and gynecology

Saheed Khan, Yvo M Smulders, Johanna I P de Vries, Angélique M E Spoelstra-de Man

Affiliations

  1. Department of Intensive Care, VU Medical Center, Postbus 7057, 1007 MB Amsterdam, The Netherlands.

PMID: 23762682 PMCID: PMC3671505 DOI: 10.1155/2013/186230

Abstract

We present a case with the rare combination of thrombotic and hemorrhagic complications of oral contraceptives. A healthy 40-year-old woman suffered from cardiac arrest due to massive pulmonary embolism, caused by oral contraceptives and immobilization during a flight. After successful resuscitation, obstructive shock necessitated thrombolysis and thereafter heparin. Anticoagulation was complicated by internal bleeding from contraceptive related hepatic adenoma. She underwent arterial embolisation, and anticoagulation was continued. On day 18, she was discharged in a good condition. Hepatic adenomas are a potential source of internal bleeding in women using oral contraceptives requiring anticoagulation. Signs of internal bleeding in such patients should prompt immediate abdominal ultrasound examination.

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