Display options
Share it on

Ann Rehabil Med. 2013 Jun;37(3):420-5. doi: 10.5535/arm.2013.37.3.420. Epub 2013 Jun 30.

A case of the cauda equina syndrome associated with the intrathecal chemotherapy in a patient with primary central nervous system lymphoma.

Annals of rehabilitation medicine

Seunglee Park, Jung-Il Kang, Hyun Bang, Bo-Ram Kim, Jongmin Lee

Affiliations

  1. Department of Rehabilitation Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.

PMID: 23869341 PMCID: PMC3713300 DOI: 10.5535/arm.2013.37.3.420

Abstract

The intrathecal chemotherapy with methotrexate and cytarabine arabinoside is used for the treatment and prophylaxis of the primary central nervous system lymphoma. The therapy may induce neurotoxicity including the cauda equina syndrome. We report a case of a 58-year-old man with the diffuse large B-cell lymphoma, who developed the cauda equina syndrome after the administration of intrathecal methotrexate and cytarabine arabinoside, as diagnosed by the electrodiagnostic, urodynamic, and radiologic approaches.

Keywords: Cauda equina syndrome; Chemotherapy; Intrathecal injections

References

  1. Ann Hematol. 2009 Mar;88(3):193-201 - PubMed
  2. N Engl J Med. 1973 Oct 11;289(15):770-3 - PubMed
  3. J Clin Oncol. 1983 Sep;1(9):546-51 - PubMed
  4. Blood. 2007 Apr 15;109(8):3214-8 - PubMed
  5. Blood. 1975 Feb;45(2):189-95 - PubMed
  6. Best Pract Res Clin Haematol. 2012 Mar;25(1):119-30 - PubMed
  7. Yonsei Med J. 2008 Feb 29;49(1):151-4 - PubMed

Publication Types