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Nan L, Jiang Z, Wei X. Emerging microfluidic devices for cell lysis: a review. Lab Chip. 2014;14(6):1060-73doi: 10.1039/c3lc51133b.
Nan, L., Jiang, Z., & Wei, X. (2014). Emerging microfluidic devices for cell lysis: a review. Lab on a chip, 14(6), 1060-73. https://doi.org/10.1039/c3lc51133b
Nan, Lang, et al. "Emerging microfluidic devices for cell lysis: a review." Lab on a chip vol. 14,6 (2014): 1060-73. doi: https://doi.org/10.1039/c3lc51133b
Nan L, Jiang Z, Wei X. Emerging microfluidic devices for cell lysis: a review. Lab Chip. 2014 Mar 21;14(6):1060-73. doi: 10.1039/c3lc51133b. PMID: 24480982.
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Lab Chip. 2014 Mar 21;14(6):1060-73. doi: 10.1039/c3lc51133b.

Emerging microfluidic devices for cell lysis: a review.

Lab on a chip

Lang Nan, Zhuangde Jiang, Xueyong Wei

Affiliations

  1. State Key Laboratory for Manufacturing Systems Engineering, Xi'An Jiaotong University, 28 Xianning West Road, 710049, Xi'An, China. [email protected].

PMID: 24480982 DOI: 10.1039/c3lc51133b

Abstract

Intracellular components containing information about genetic and disease characteristics are key substances to clinical diagnostics. Cell lysis is therefore a crucial step for efficient extraction and the subsequent analysis of intracellular components. With the advent of advanced manufacturing techniques, a number of micro systems have been proposed and applied for manipulating cells on chips. In this paper, we review emerging microfluidic devices for cell lysis. Different lysis mechanisms and related techniques are compared. The technical details, advantages, and limitations of various microfluidic devices are discussed.

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