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Gajos-Michniewicz A, Duechler M, Czyz M. MiRNA in melanoma-derived exosomes. Cancer Lett. 2014;347(1):29-37doi: 10.1016/j.canlet.2014.02.004.
Gajos-Michniewicz, A., Duechler, M., & Czyz, M. (2014). MiRNA in melanoma-derived exosomes. Cancer letters, 347(1), 29-37. https://doi.org/10.1016/j.canlet.2014.02.004
Gajos-Michniewicz, Anna, et al. "MiRNA in melanoma-derived exosomes." Cancer letters vol. 347,1 (2014): 29-37. doi: https://doi.org/10.1016/j.canlet.2014.02.004
Gajos-Michniewicz A, Duechler M, Czyz M. MiRNA in melanoma-derived exosomes. Cancer Lett. 2014 May 28;347(1):29-37. doi: 10.1016/j.canlet.2014.02.004. Epub 2014 Feb 07. PMID: 24513178.
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Cancer Lett. 2014 May 28;347(1):29-37. doi: 10.1016/j.canlet.2014.02.004. Epub 2014 Feb 07.

MiRNA in melanoma-derived exosomes.

Cancer letters

Anna Gajos-Michniewicz, Markus Duechler, Malgorzata Czyz

Affiliations

  1. Department of Molecular Biology of Cancer, Medical University of Lodz, Poland.
  2. Department of Bioorganic Chemistry, Centre for Molecular and Macromolecular Studies, Polish Academy of Sciences, Lodz, Poland.
  3. Department of Molecular Biology of Cancer, Medical University of Lodz, Poland. Electronic address: [email protected].

PMID: 24513178 DOI: 10.1016/j.canlet.2014.02.004

Abstract

Proteins, RNAs and viruses can be spread through exosomes, therefore transport utilizing these nanovesicles is of the great interest. MiRNAs are common exosomal constituents capable of influencing expression of a variety of target genes. MiRNA signatures of exosomes are unique in cancer patients and differ from those in normal controls. The knowledge about miRNA profiles of tumor-derived exosomes may contribute to better diagnosis, determination of tumor progression and response to treatment, as well as to the development of targeted therapies. We summarize the current knowledge with regard to miRNAs that are found in exosomes derived from tumors, particularly from melanoma.

Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Keywords: Biomarker; Exosome; Melanoma; MiRNA; MicroRNA

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