Display options
Share it on

J Diabetes Metab Disord. 2014 Mar 06;13(1):44. doi: 10.1186/2251-6581-13-44.

Association between psychosocial distress with cardio metabolic risk factors and liver enzymes in a nationally-representative sample of Iranian children and adolescents: the CASPIAN-III study.

Journal of diabetes and metabolic disorders

Mostafa Qorbani, Roya Kelishadi, Ehsaneh Taheri, Mohammad Esmaeil Motlagh, Seyed Masoud Arzaghi, Gelayol Ardalan, Mohammad Chinian, Minoosadat Mahmoudarabi, Aziz Rezapoor, Hamid Asayesh, Bagher Larijani, Mohammad Reza Amini, Ramin Heshmat

Affiliations

  1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. [email protected].

PMID: 24602504 PMCID: PMC3975638 DOI: 10.1186/2251-6581-13-44

Abstract

BACKGROUND: The present study was designed to evaluate association of psychosocial distress with cardio metabolic risk factors and liver enzymes in Iranian children and adolescents.

METHOD: This nationwide study was conducted as the third survey of the school-based surveillance system that was conducted among 5593 school students, 10-18 years in Iran. High triglyceride (TG), high fasting blood sugar (FBS), high total cholesterol (TC), high low-density lipoprotein cholesterol (LDL-C), low high-density lipoprotein cholesterol (HDL-C), hypertension (HTN), generalized obesity and abdominal obesity were considered as cardio metabolic risk factors and alanine transaminase (ALT) and aspartate aminotransferase (AST) were considered as liver enzymes. Data were analyzed using multiple logistic regression (MLR) analysis.

RESULT: Psychosocial distress was detected in2027 (71.2%) of boys and 1759 (63.3%) of girls. Among boys, the mean of LDL, AST and DBP were higher and the mean FBS and HDL were lowering those with psychiatric distress than their other counterparts. Girls with psychosocial distress had significantly higher mean of HDL and FBS than those without psychiatric distress. Psychosocial distress significantly increased the odds of high LDL (OR = 2.36, 95%CI 1.53, 3.64), high FBS (OR = 1.23, 95%CI 1.02, 1.49) and low HDL (OR = 1.65, 95%CI 1.41, 1.95).

CONCLUSION: Psychosocial distress in adolescents is associated with increased risk of some cardio metabolic risk factors.

References

  1. J Clin Hypertens (Greenwich). 2012 Jun;14(6):360-4 - PubMed
  2. Psychosom Med. 2004 May-Jun;66(3):316-22 - PubMed
  3. Acta Med Iran. 2012;50(3):177-84 - PubMed
  4. Southeast Asian J Trop Med Public Health. 2012 May;43(3):756-63 - PubMed
  5. Prim Care Companion CNS Disord. 2012;14(1): - PubMed
  6. Health Psychol. 2009 Jan;28(1):108-16 - PubMed
  7. J Am Acad Child Adolesc Psychiatry. 2003 Oct;42(10):1203-11 - PubMed
  8. Eur J Appl Physiol. 2013 Mar;113(3):671-9 - PubMed
  9. J Epidemiol Community Health. 2012 Aug;66(8):691-7 - PubMed
  10. Diabetes Care. 2009 Mar;32(3):499-504 - PubMed
  11. Br J Nutr. 2000 Mar;83 Suppl 1:S49-57 - PubMed
  12. Metabolism. 2002 Dec;51(12):1573-7 - PubMed
  13. J Clin Psychiatry. 2006 Sep;67(9):1422-7 - PubMed
  14. Circulation. 2011 Jun 14;123(23):2749-69 - PubMed
  15. Eur Psychiatry. 2009 Sep;24(6):412-24 - PubMed
  16. Soc Sci Med. 2007 Jan;64(1):5-20 - PubMed
  17. Br J Psychiatry. 2004 Jan;184:70-3 - PubMed
  18. Diabetes Care. 2007 Apr;30(4):872-7 - PubMed
  19. J Adolesc Health. 2007 Dec;41(6):571-6 - PubMed
  20. J Pediatr Gastroenterol Nutr. 2014 Apr;58(4):463-8 - PubMed
  21. Clin Chem. 1972 Jun;18(6):499-502 - PubMed
  22. Hepat Mon. 2012 Nov;12(11):e7711 - PubMed
  23. Kardiol Pol. 2006 May;64(5):464-9 - PubMed
  24. Int J Hypertens. 2011 Jan 24;2011:931402 - PubMed
  25. Int J Endocrinol. 2013;2013:702095 - PubMed
  26. Int J Prev Med. 2012 Jun;3(6):394-401 - PubMed
  27. J Clin Psychiatry. 2008 Feb;69(2):178-82 - PubMed

Publication Types