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Ostuzzi G, Barbui C. Autism spectrum disorders: weighing the risk of SSRI exposure in pregnancy. Epidemiol Psychiatr Sci. 2014;23(3):231-3doi: 10.1017/S2045796014000286.
Ostuzzi, G., & Barbui, C. (2014). Autism spectrum disorders: weighing the risk of SSRI exposure in pregnancy. Epidemiology and psychiatric sciences, 23(3), 231-3. https://doi.org/10.1017/S2045796014000286
Ostuzzi, G, and Barbui, C. "Autism spectrum disorders: weighing the risk of SSRI exposure in pregnancy." Epidemiology and psychiatric sciences vol. 23,3 (2014): 231-3. doi: https://doi.org/10.1017/S2045796014000286
Ostuzzi G, Barbui C. Autism spectrum disorders: weighing the risk of SSRI exposure in pregnancy. Epidemiol Psychiatr Sci. 2014 Sep;23(3):231-3. doi: 10.1017/S2045796014000286. Epub 2014 May 01. PMID: 24786563; PMCID: PMC6998250.
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Epidemiol Psychiatr Sci. 2014 Sep;23(3):231-3. doi: 10.1017/S2045796014000286. Epub 2014 May 01.

Autism spectrum disorders: weighing the risk of SSRI exposure in pregnancy.

Epidemiology and psychiatric sciences

G Ostuzzi, C Barbui

Affiliations

  1. Department of Public Health and Community Medicine, Section of Psychiatry,University of Verona,Verona,Italy.

PMID: 24786563 PMCID: PMC6998250 DOI: 10.1017/S2045796014000286

Abstract

A possible link between prenatal exposure to the selective serotonin reuptake inhibitors (SSRIs) and development of autism spectrum disorders (ASDs), previously suggested by two case-control studies, was not confirmed by a recent cohort study that followed for 5-10 years more than 600,000 births. However, this study failed to demonstrate that SSRI exposure during pregnancy is safe in terms of child development outcomes, as an increased risk of ASDs cannot be completely ruled out. In the present article, the main strengths and weaknesses of this study are briefly analysed, including a possibility of confounding by indication.

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