Display options
Cite
Morris MJ, Woodcock EA. Postnatal development of rat alpha- and beta-adrenergic receptors: A comparison between tissues. Int J Dev Neurosci. 1983;1(1):35-42doi: 10.1016/0736-5748(83)90008-4.
Morris, M. J., & Woodcock, E. A. (1983). Postnatal development of rat alpha- and beta-adrenergic receptors: A comparison between tissues. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1(1), 35-42. https://doi.org/10.1016/0736-5748(83)90008-4
Morris, M J, and Woodcock, E A. "Postnatal development of rat alpha- and beta-adrenergic receptors: A comparison between tissues." International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience vol. 1,1 (1983): 35-42. doi: https://doi.org/10.1016/0736-5748(83)90008-4
Morris MJ, Woodcock EA. Postnatal development of rat alpha- and beta-adrenergic receptors: A comparison between tissues. Int J Dev Neurosci. 1983;1(1):35-42. doi: 10.1016/0736-5748(83)90008-4. PMID: 24875604.
Copy Download .nbib Format: NLM
Share it on

Int J Dev Neurosci. 1983;1(1):35-42. doi: 10.1016/0736-5748(83)90008-4.

Postnatal development of rat alpha- and beta-adrenergic receptors: A comparison between tissues.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

M J Morris, E A Woodcock

Affiliations

  1. Monash University Department of Medicine, Prince Henry's Hospital, St. Kilda Road, Melbourne, Victoria 3004, Australia.

PMID: 24875604 DOI: 10.1016/0736-5748(83)90008-4

Abstract

The rates of development of rat kidney α- and β-adrenoceptors were compared with those of heart and lung adrenoceptors in the same animals by direct binding studies using [(3)H]WB4101 (α1), [(3)H]yohimbine (α2) and [(125)I]HYP (β). Kidney α1 and β-adrenoceptors had reached adult concentrations 7 days after birth, while the α2-adrenoceptor concentration plateaued at 21 days. Lung β-adrenoceptor concentration was stable initially, then increased rapidly to adult levels by 18 days. In contrast, heart α1-and β-adrenoceptor concentrations were at mature levels at birth. In all tissues studied the increase in noradrenaline concentration was slower than the increases in adrenoceptor concentrations.

Copyright © 1983. Published by Elsevier Ltd.

Publication Types