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Lin AJ, Liu G, Castello NA, et al. Optical imaging in an Alzheimer's mouse model reveals amyloid- β-dependent vascular impairment. Neurophotonics. 2014;1(1):011005doi: 10.1117/1.NPh.1.1.011005.
Lin, A. J., Liu, G., Castello, N. A., Yeh, J. J., Rahimian, R., Lee, G., Tsay, V., Durkin, A. J., Choi, B., LaFerla, F. M., Chen, Z., Green, K. N., & Tromberg, B. J. (2014). Optical imaging in an Alzheimer's mouse model reveals amyloid- β-dependent vascular impairment. Neurophotonics, 1(1), 011005. https://doi.org/10.1117/1.NPh.1.1.011005
Lin, Alexander J, et al. "Optical imaging in an Alzheimer's mouse model reveals amyloid- β-dependent vascular impairment." Neurophotonics vol. 1,1 (2014): 011005. doi: https://doi.org/10.1117/1.NPh.1.1.011005
Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green KN, Tromberg BJ. Optical imaging in an Alzheimer's mouse model reveals amyloid- β-dependent vascular impairment. Neurophotonics. 2014 Jul;1(1):011005. doi: 10.1117/1.NPh.1.1.011005. PMID: 25133200; PMCID: PMC4132842.
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Neurophotonics. 2014 Jul;1(1):011005. doi: 10.1117/1.NPh.1.1.011005.

Optical imaging in an Alzheimer's mouse model reveals amyloid- β-dependent vascular impairment.

Neurophotonics

Alexander J Lin, Gangjun Liu, Nicholas A Castello, James J Yeh, Rombod Rahimian, Grace Lee, Victoria Tsay, Anthony J Durkin, Bernard Choi, Frank M LaFerla, Zhongping Chen, Kim N Green, Bruce J Tromberg

Affiliations

  1. Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program, 1002 Health Sciences Road, Irvine, California 92612 ; University of California Irvine, Department of Biomedical Engineering, 3120 Natural Sciences II, Irvine, California 92697-2715.
  2. Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program, 1002 Health Sciences Road, Irvine, California 92612.
  3. University of California Irvine, Institute for Memory Impairments and Neurological Disorders, 2642 Biological Sciences III Irvine, California 92697-4545 ; University of California Irvine, Department of Neurobiology and Behavior, 2205 McGaugh Hall, Irvine, California 92697-4550.

PMID: 25133200 PMCID: PMC4132842 DOI: 10.1117/1.NPh.1.1.011005

Abstract

Alzheimer's disease (AD) and cerebrovascular disease are often comorbid conditions, but the relationship between amyloid-

Keywords: Doppler optical coherence tomography; absorption; diffuse optical spectroscopy; hypercapnia; microvascular perfusion; neuroimaging; scattering; spatial frequency domain imaging; vascular reactivity

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