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Porwal B, Jayashree BS, Attimarad M. Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity. J Basic Clin Pharm. 2010;1(1):29-32
Porwal, B., Jayashree, B. S., & Attimarad, M. (2009). Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity. Journal of basic and clinical pharmacy, 1(1), 29-32.
Porwal, Brajesh, et al. "Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity." Journal of basic and clinical pharmacy vol. 1,1 (2009): 29-32.
Porwal B, Jayashree BS, Attimarad M. Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity. J Basic Clin Pharm. 2009 Dec;1(1):29-32. Epub 2010 Feb 15. PMID: 25206250; PMCID: PMC4158894.
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J Basic Clin Pharm. 2009 Dec;1(1):29-32. Epub 2010 Feb 15.

Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity.

Journal of basic and clinical pharmacy

Brajesh Porwal, B S Jayashree, Mahesh Attimarad

Affiliations

  1. Department of Pharmaceutical Chemistry, Al-Ameen College of Pharmacy, Hosur Road, Bangalore, India.
  2. Department of Pharmaceutical chemistry, College of Pharmaceutical Sciences, Manipal, India.
  3. College of Clinical Pharmacy, King Faisal University, Al-Hasa, KSA.

PMID: 25206250 PMCID: PMC4158894

Abstract

3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their spectral data. The antimicrobial activitiy of all the newly synthesized test compounds were evaluated and some of them, showed good antibacterial activity.

Keywords: Antimicrobial Activity; Coumarins

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