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Showing 1 to 12 of 25 entries
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Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity.

Journal of basic and clinical pharmacy

Porwal B, Jayashree BS, Attimarad M.
PMID: 25206250
J Basic Clin Pharm. 2009 Dec;1(1):29-32. Epub 2010 Feb 15.

3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established...

Plant metobolomics - A novel method in phytochemical analysis.

Pharmaceutical methods

Mueen AK, Madkor H, Attimarad M, Khan TM.
PMID: 23781420
Pharm Methods. 2010 Oct;1(1):65-6. doi: 10.4103/2229-4708.72235.

No abstract available.

Simultaneous determination of paracetamol and lornoxicam by RP-HPLC in bulk and tablet formulation.

Pharmaceutical methods

Attimarad M.
PMID: 23781432
Pharm Methods. 2011 Jan;2(1):61-6. doi: 10.4103/2229-4708.81084.

AIM: The objective of the study was to develop simple RP-HPLC method for the simultaneous determination of paracetamol and lornoxicam without prior separation.MATERIALS AND METHODS: In this method, Kromasil C8 (250 mm, 4.6 mm, 5 μm) column was used....

Mucoadhesive buccal film of almotriptan improved therapeutic delivery in rabbit model.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Nair AB, Al-Dhubiab BE, Shah J, Jacob S, Saraiya V, Attimarad M, SreeHarsha N, Akrawi SH, Shehata TM.
PMID: 32042259
Saudi Pharm J. 2020 Feb;28(2):201-209. doi: 10.1016/j.jsps.2019.11.022. Epub 2019 Dec 07.

Administration of almotriptan as an oral therapy is largely limited because of poor aqueous solubility and rather low bioavailability. The aim of present investigation was to formulate oral mucoadhesive film of almotriptan to improve the drug delivery and desired...

Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification.

Antibiotics (Basel, Switzerland)

Venugopala KN, Tratrat C, Pillay M, Mahomoodally FM, Bhandary S, Chopra D, Morsy MA, Haroun M, Aldhubiab BE, Attimarad M, Nair AB, Sreeharsha N, Venugopala R, Chandrashekharappa S, Alwassil OI, Odhav B.
PMID: 31816928
Antibiotics (Basel). 2019 Dec 03;8(4). doi: 10.3390/antibiotics8040247.

Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of

High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery.

Pharmaceutical methods

Attimarad M, Ahmed KK, Aldhubaib BE, Harsha S.
PMID: 23781433
Pharm Methods. 2011 Apr;2(2):71-5. doi: 10.4103/2229-4708.84436.

Analysis of pharmaceutical and natural compounds and newer drugs is commonly used in all the stages of drug discovery and development process. High-performance thin layer chromatography is one of the sophisticated instrumental techniques based on the full capabilities of...

Cytotoxicity and Antimycobacterial Properties of Pyrrolo[1,2-.

Antibiotics (Basel, Switzerland)

Venugopala KN, Uppar V, Chandrashekharappa S, Abdallah HH, Pillay M, Deb PK, Morsy MA, Aldhubiab BE, Attimarad M, Nair AB, Sreeharsha N, Tratrat C, Yousef Jaber A, Venugopala R, Mailavaram RP, Al-Jaidi BA, Kandeel M, Haroun M, Padmashali B.
PMID: 32392709
Antibiotics (Basel). 2020 May 07;9(5). doi: 10.3390/antibiotics9050233.

A series of ethyl 1-(substituted benzoyl)-5-methylpyrrolo[1,2-

Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic.

Nanomaterials (Basel, Switzerland)

Asdaq SMB, Ikbal AMA, Sahu RK, Bhattacharjee B, Paul T, Deka B, Fattepur S, Widyowati R, Vijaya J, Al Mohaini M, Alsalman AJ, Imran M, Nagaraja S, Nair AB, Attimarad M, Venugopala KN.
PMID: 34361227
Nanomaterials (Basel). 2021 Jul 16;11(7). doi: 10.3390/nano11071841.

The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of...

Topical Nanoemulgel for the Treatment of Skin Cancer: Proof-of-Technology.

Pharmaceutics

Nagaraja S, Basavarajappa GM, Attimarad M, Pund S.
PMID: 34207014
Pharmaceutics. 2021 Jun 18;13(6). doi: 10.3390/pharmaceutics13060902.

The present study is a mechanistic validation of 'proof-of-technology' for the effective topical delivery of chrysin nanoemulgel for localized, efficient treatment of melanoma-affected skin.BACKGROUND: Currently available treatments for skin cancer are inefficient due to systemic side effects and poor...

A conventional HPLC-MS method for the simultaneous determination of ofloxacin and cefixime in plasma: Development and validation.

Journal of basic and clinical pharmacy

Attimarad MV, Alnajjar AO.
PMID: 24808668
J Basic Clin Pharm. 2013 Mar;4(2):36-41. doi: 10.4103/0976-0105.113606.

OBJECTIVE: A simple, rapid, and sensitive high performance liquid chromatography-mass spectrometry (HPLC-MS) method was developed and validated for the simultaneous determination of ofloxacin (OFL) and cefixime (CEF) in human plasma using the moxifloxacin as internal standard.METHODOLOGY: Analytes were separated...

Simultaneous Determination of Ofloxacin and Flavoxate Hydrochloride by Absorption Ratio and Second Derivative UV Spectrophotometry.

Journal of basic and clinical pharmacy

Attimarad M.
PMID: 24826003
J Basic Clin Pharm. 2010 Dec;2(1):53-61. Epub 2011 Feb 15.

The objective of this study was to develop simple, precise, accurate and sensitive UV spectrophotometric methods for the simultaneous determination of ofloxacin (OFX) and flavoxate HCl (FLX) in pharmaceutical formulations. The first method is based on absorption ratio method,...

Rapid rp HPLC method for quantitative determination of lornoxicam in tablets.

Journal of basic and clinical pharmacy

Attimarad M.
PMID: 24825976
J Basic Clin Pharm. 2010 Mar;1(2):115-8. Epub 2010 May 15.

The objective of the study was to develop a simple, rapid, specific and precise reverse phase high performance liquid chromatographic method for the determination of lornoxicam in bulk and pharmaceutical preparations. Chromatographic separation of the drug was performed on...

Showing 1 to 12 of 25 entries