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Liu KD, Wilson JG, Zhuo H, et al. Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Ann Intensive Care. 2014;4:22doi: 10.1186/s13613-014-0022-z.
Liu, K. D., Wilson, J. G., Zhuo, H., Caballero, L., McMillan, M. L., Fang, X., Cosgrove, K., Calfee, C. S., Lee, J. W., Kangelaris, K. N., Gotts, J. E., Rogers, A. J., Levitt, J. E., Wiener-Kronish, J. P., Delucchi, K. L., Leavitt, A. D., McKenna, D. H., Thompson, B. T., & Matthay, M. A. (2014). Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Annals of intensive care, 422. https://doi.org/10.1186/s13613-014-0022-z
Liu, Kathleen D, et al. "Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome." Annals of intensive care vol. 4 (2014): 22. doi: https://doi.org/10.1186/s13613-014-0022-z
Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA. Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Ann Intensive Care. 2014 Jul 03;4:22. doi: 10.1186/s13613-014-0022-z. eCollection 2014. PMID: 25593740; PMCID: PMC4273700.
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Ann Intensive Care. 2014 Jul 03;4:22. doi: 10.1186/s13613-014-0022-z. eCollection 2014.

Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome.

Annals of intensive care

Kathleen D Liu, Jennifer G Wilson, Hanjing Zhuo, Lizette Caballero, Melanie L McMillan, Xiaohui Fang, Katherine Cosgrove, Carolyn S Calfee, Jae-Woo Lee, Kirsten N Kangelaris, Jeffrey E Gotts, Angela J Rogers, Joseph E Levitt, Jeanine P Wiener-Kronish, Kevin L Delucchi, Andrew D Leavitt, David H McKenna, B Taylor Thompson, Michael A Matthay

Affiliations

  1. Departments of Nephrology and Anesthesia, University of California, San Francisco, CA, USA.
  2. Departments of Emergency Medicine and Critical Care Medicine, University of California, San Francisco, CA, USA.
  3. Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
  4. Clinical Laboratories, Bone Marrow Center, University of California, San Francisco, CA, USA.
  5. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  6. Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA, USA.
  7. Department of Anesthesia, University of California, San Francisco, CA, USA.
  8. Division of Hospital Medicine, Department of Medicine, University of California, San Francisco, CA, USA.
  9. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
  10. Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Cambridge, MA, USA.
  11. Department of Psychiatry, University of California, San Francisco, CA, USA.
  12. Department of Laboratory Medicine, University of California, San Francisco, CA, USA.
  13. Division of Transfusion Medicine, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
  14. Departments of Medicine and Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, CA, USA.

PMID: 25593740 PMCID: PMC4273700 DOI: 10.1186/s13613-014-0022-z

Abstract

CLINICAL TRIALS REGISTRATION: NCT01775774 and NCT02097641.

Keywords: Acute lung injury; Clinical trial; Mesenchymal stem/stromal cell; Pulmonary edema

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