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Thomas S, Ghosh J, Porter J, et al. Periodontal disease and late-onset aortic prosthetic vascular graft infection. Case Rep Vasc Med. 2015;2015:768935doi: 10.1155/2015/768935.
Thomas, S., Ghosh, J., Porter, J., Cockcroft, A., & Rautemaa-Richardson, R. (2015). Periodontal disease and late-onset aortic prosthetic vascular graft infection. Case reports in vascular medicine, 2015768935. https://doi.org/10.1155/2015/768935
Thomas, Stephanie, et al. "Periodontal disease and late-onset aortic prosthetic vascular graft infection." Case reports in vascular medicine vol. 2015 (2015): 768935. doi: https://doi.org/10.1155/2015/768935
Thomas S, Ghosh J, Porter J, Cockcroft A, Rautemaa-Richardson R. Periodontal disease and late-onset aortic prosthetic vascular graft infection. Case Rep Vasc Med. 2015;2015:768935. doi: 10.1155/2015/768935. Epub 2015 Jan 21. PMID: 25685592; PMCID: PMC4320805.
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Case Rep Vasc Med. 2015;2015:768935. doi: 10.1155/2015/768935. Epub 2015 Jan 21.

Periodontal disease and late-onset aortic prosthetic vascular graft infection.

Case reports in vascular medicine

Stephanie Thomas, Jonathan Ghosh, Johnathan Porter, Adele Cockcroft, Riina Rautemaa-Richardson

Affiliations

  1. Department of Microbiology, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.
  2. Department of Vascular Surgery, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.
  3. Department of Microbiology, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK ; The University of Manchester, Manchester Academic Health Science Centre, Institute of Inflammation and Repair, Oxford Road, Manchester M13 9PT, UK.

PMID: 25685592 PMCID: PMC4320805 DOI: 10.1155/2015/768935

Abstract

Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI.

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