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Han SY, Lee SI, Lee YH, et al. IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor. Chonnam Med J. 2015;51(1):39-42doi: 10.4068/cmj.2015.51.1.39.
Han, S. Y., Lee, S. I., Lee, Y. H., Kim, A. J., Lim, H. J., Ro, H., Chang, J. H., Lee, H. H., Chung, W., & Jung, J. Y. (2015). IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor. Chonnam medical journal, 51(1), 39-42. https://doi.org/10.4068/cmj.2015.51.1.39
Han, Song Yi, et al. "IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor." Chonnam medical journal vol. 51,1 (2015): 39-42. doi: https://doi.org/10.4068/cmj.2015.51.1.39
Han SY, Lee SI, Lee YH, Kim AJ, Lim HJ, Ro H, Chang JH, Lee HH, Chung W, Jung JY. IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor. Chonnam Med J. 2015 Apr;51(1):39-42. doi: 10.4068/cmj.2015.51.1.39. Epub 2015 Apr 14. PMID: 25914879; PMCID: PMC4406993.
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Chonnam Med J. 2015 Apr;51(1):39-42. doi: 10.4068/cmj.2015.51.1.39. Epub 2015 Apr 14.

IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor.

Chonnam medical journal

Song Yi Han, Seung Ik Lee, Yeon Hee Lee, Ae Jin Kim, Hye Jin Lim, Han Ro, Jae Hyun Chang, Hyun Hee Lee, Wookyung Chung, Ji Yong Jung

Affiliations

  1. Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
  2. Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea. ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.

PMID: 25914879 PMCID: PMC4406993 DOI: 10.4068/cmj.2015.51.1.39

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic syndrome characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltration by IgG4-positive plasma cells. We experienced a case of IgG4-RD involving multiple organs in a 64-year-old female who was referred for a suspected uroepithelial tumor. A mass biopsy confirmed dense lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. We discuss this case and review the literature to bring IgG4-RD to the attention to clinicians because it responds dramatically well to steroid therapy and should be kept in mind as a differential diagnosis to avoid unnecessary surgery.

Keywords: Immunoglobulin G; Kidney; Sclerosis

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