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Tumour Biol. 2015 May;36(5):3179-89. doi: 10.1007/s13277-015-3384-4. Epub 2015 Apr 03.

Note of clarification of data in the paper titled X-ray repair cross-complementing group 1 codon 399 polymorphism and lung cancer risk: an updated meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wenlong Zhai, Ruo Feng, Haiyu Wang, Yadong Wang

Affiliations

  1. Department of General Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.

PMID: 25835974 DOI: 10.1007/s13277-015-3384-4

Abstract

We read with great interest the paper titled "X-ray repair cross-complementing group 1 codon 399 polymorphism and lung cancer risk: an updated meta-analysis" published by Wang et al in Tumor Biology, 2014, 35:411-418. Their results suggest that codon 399 polymorphism of XRCC1 gene might contribute to individual's susceptibility to lung cancer in Asian population and especially in nonsmoking Chinese women. The result is encouraging. Nevertheless, several key issues are worth noticing.

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