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Rettmann ME, Holmes DR, Johnson SB, et al. Analysis of Left Atrial Respiratory and Cardiac Motion for Cardiac Ablation Therapy. Proc SPIE Int Soc Opt Eng. 2015;9415doi: 10.1117/12.2081209.
Rettmann, M. E., Holmes, D. R., Johnson, S. B., Lehmann, H. I., Robb, R. A., & Packer, D. L. (2015). Analysis of Left Atrial Respiratory and Cardiac Motion for Cardiac Ablation Therapy. Proceedings of SPIE--the International Society for Optical Engineering, 9415. https://doi.org/10.1117/12.2081209
Rettmann, M E, et al. "Analysis of Left Atrial Respiratory and Cardiac Motion for Cardiac Ablation Therapy." Proceedings of SPIE--the International Society for Optical Engineering vol. 9415 (2015). doi: https://doi.org/10.1117/12.2081209
Rettmann ME, Holmes DR, Johnson SB, Lehmann HI, Robb RA, Packer DL. Analysis of Left Atrial Respiratory and Cardiac Motion for Cardiac Ablation Therapy. Proc SPIE Int Soc Opt Eng. 2015 Feb 21;9415. doi: 10.1117/12.2081209. PMID: 26405370; PMCID: PMC4576347.
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Proc SPIE Int Soc Opt Eng. 2015 Feb 21;9415. doi: 10.1117/12.2081209.

Analysis of Left Atrial Respiratory and Cardiac Motion for Cardiac Ablation Therapy.

Proceedings of SPIE--the International Society for Optical Engineering

M E Rettmann, D R Holmes, S B Johnson, H I Lehmann, R A Robb, D L Packer

Affiliations

  1. Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 55905, USA.
  2. Biomedical Imaging Resource, Mayo Clinic, Rochester, Minnesota, 55905, USA.

PMID: 26405370 PMCID: PMC4576347 DOI: 10.1117/12.2081209

Abstract

Cardiac ablation therapy is often guided by models built from preoperative computed tomography (CT) or magnetic resonance imaging (MRI) scans. One of the challenges in guiding a procedure from a preoperative model is properly synching the preoperative models with cardiac and respiratory motion through computational motion models. In this paper, we describe a methodology for evaluating cardiac and respiratory motion in the left atrium and pulmonary veins of a beating canine heart. Cardiac catheters were used to place metal clips within and near the pulmonary veins and left atrial appendage under fluoroscopic and ultrasound guidance and a contrast-enhanced, 64-slice multidetector CT scan was collected with the clips in place. Each clip was segmented from the CT scan at each of the five phases of the cardiac cycle at both end-inspiration and end-expiration. The centroid of each segmented clip was computed and used to evaluate both cardiac and respiratory motion of the left atrium. A total of three canine studies were completed, with 4 clips analyzed in the first study, 5 clips in the second study, and 2 clips in the third study. Mean respiratory displacement was 0.2±1.8

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