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Liu C, Haynes PR, Donelson NC, et al. Sleep in Populations of Drosophila Melanogaster. eNeuro. 2015;2(4)doi: 10.1523/ENEURO.0071-15.2015.
Liu, C., Haynes, P. R., Donelson, N. C., Aharon, S., & Griffith, L. C. (2015). Sleep in Populations of Drosophila Melanogaster. eNeuro, 2(4), . https://doi.org/10.1523/ENEURO.0071-15.2015
Liu, Chang, et al. "Sleep in Populations of Drosophila Melanogaster." eNeuro vol. 2,4 (2015). doi: https://doi.org/10.1523/ENEURO.0071-15.2015
Liu C, Haynes PR, Donelson NC, Aharon S, Griffith LC. Sleep in Populations of Drosophila Melanogaster. eNeuro. 2015 Aug 21;2(4). doi: 10.1523/ENEURO.0071-15.2015. eCollection 2015. PMID: 26465005; PMCID: PMC4596024.
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eNeuro. 2015 Aug 21;2(4). doi: 10.1523/ENEURO.0071-15.2015. eCollection 2015.

Sleep in Populations of Drosophila Melanogaster.

eNeuro

Chang Liu, Paula R Haynes, Nathan C Donelson, Shani Aharon, Leslie C Griffith

Affiliations

  1. Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University , Waltham, Massachusetts 02454-9110.

PMID: 26465005 PMCID: PMC4596024 DOI: 10.1523/ENEURO.0071-15.2015

Abstract

The fruit fly Drosophila melanogaster is a diurnal insect active during the day with consolidated sleep at night. Social interactions between pairs of flies have been shown to affect locomotor activity patterns, but effects on locomotion and sleep patterns have not been assessed for larger populations. Here, we use a commercially available locomotor activity monitor (LAM25H) system to record and analyze sleep behavior. Surprisingly, we find that same-sex populations of flies synchronize their sleep/wake activity, resulting in a population sleep pattern, which is similar but not identical to that of isolated individuals. Like individual flies, groups of flies show circadian and homeostatic regulation of sleep, as well as sexual dimorphism in sleep pattern and sensitivity to starvation and a known sleep-disrupting mutation (amnesiac). Populations of flies, however, exhibit distinct sleep characteristics from individuals. Differences in sleep appear to be due to olfaction-dependent social interactions and change with population size and sex ratio. These data support the idea that it is possible to investigate neural mechanisms underlying the effects of population behaviors on sleep by directly looking at a large number of animals in laboratory conditions.

Keywords: Drosophila; population; sleep

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