Display options
Cite
Ma Y, Gui Q, Lang S. Intracranial malignant melanoma: A report of 7 cases. Oncol Lett. 2015;10(4):2171-2175doi: 10.3892/ol.2015.3537.
Ma, Y., Gui, Q., & Lang, S. (2015). Intracranial malignant melanoma: A report of 7 cases. Oncology letters, 10(4), 2171-2175. https://doi.org/10.3892/ol.2015.3537
Ma, Yunfeng, et al. "Intracranial malignant melanoma: A report of 7 cases." Oncology letters vol. 10,4 (2015): 2171-2175. doi: https://doi.org/10.3892/ol.2015.3537
Ma Y, Gui Q, Lang S. Intracranial malignant melanoma: A report of 7 cases. Oncol Lett. 2015 Oct;10(4):2171-2175. doi: 10.3892/ol.2015.3537. Epub 2015 Jul 24. PMID: 26622814; PMCID: PMC4579826.
Copy Download .nbib Format: NLM
Share it on

Oncol Lett. 2015 Oct;10(4):2171-2175. doi: 10.3892/ol.2015.3537. Epub 2015 Jul 24.

Intracranial malignant melanoma: A report of 7 cases.

Oncology letters

Yunfeng Ma, Qiuping Gui, Senyang Lang

Affiliations

  1. Department of Neurology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
  2. Department of Pathology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
  3. Department of Psychology, Chinese PLA General Hospital, Beijing 100853, P.R. China.

PMID: 26622814 PMCID: PMC4579826 DOI: 10.3892/ol.2015.3537

Abstract

The aim of the present study was to investigate the clinical diagnosis and treatment of intracranial malignant melanoma. For this purpose, the clinical manifestation, signs, cerebrospinal fluid (CSF) contents, imageology, pathological features, treatment and prognosis of 7 cases of intracranial malignant melanoma were analyzed in The Chinese PLA General Hospital (Beijing, China) from 1996 to 2013. All the melanoma cases were confirmed by histopathology, and CSF cytopathology demonstrated that there were 5 cases of primary malignant melanoma and 2 cases of secondary malignant melanoma. Among the patients, 4 presented with >1 pigmented nevus in the skin, and 1 presented with skin melanoma. Intracranial malignant melanoma mostly affects middle-aged males. CSF cytopathology and imageology (particularly enhanced magnetic resonance), are important tools in the diagnosis of the disease. Particularly, when a patient presents with a pigmented nevus in the skin and an abnormal lesion in the brain, a diagnosis of intracranial malignant melanoma should be considered.

Keywords: CNS; CSF cytological pathology; imageology; malignant melanoma

References

  1. J Coll Physicians Surg Pak. 2013 Feb;23(2):157-9 - PubMed
  2. J Neurosurg. 2004 Sep;101(3):528-31 - PubMed
  3. Curr Opin Oncol. 2004 Mar;16(2):161-6 - PubMed
  4. J Neurosurg. 1998 Oct;89(4):659-66 - PubMed
  5. J Neurooncol. 2006 May;77(3):311-4 - PubMed
  6. Melanoma Res. 2005 Oct;15(5):467-9 - PubMed
  7. Clin Neurol Neurosurg. 2011 Jan;113(1):59-64 - PubMed
  8. Cancer. 2004 Jun 1;100(11):2442-7 - PubMed
  9. AJR Am J Roentgenol. 1995 Dec;165(6):1503-12 - PubMed
  10. Acta Neuropathol. 2012 Mar;123(3):457-9 - PubMed
  11. Acta Oncol. 1989;28(1):103-4 - PubMed
  12. N Engl J Med. 2008 Jun 19;358(25):2698-703 - PubMed
  13. Brain Tumor Pathol. 2003;20(1):21-5 - PubMed
  14. J Clin Neuroophthalmol. 1990 Mar;10(1):41-4 - PubMed
  15. J Clin Neurosci. 2010 Oct;17(10):1227-32 - PubMed
  16. Ann Clin Biochem. 2004 Mar;41(Pt 2):162-5 - PubMed
  17. Semin Oncol. 2002 Oct;29(5):518-24 - PubMed
  18. J Neurooncol. 2003 Sep;64(3):259-63 - PubMed
  19. Turk Neurosurg. 2012;22(4):469-74 - PubMed
  20. J Neurosurg. 2002 Mar;96(3):544-51 - PubMed
  21. J Neurosurg Spine. 2007 May;6(5):451-4 - PubMed
  22. Neurosurgery. 1993 May;32(5):721-9; discussion 729 - PubMed
  23. Acta Neuropathol. 2010 Mar;119(3):317-23 - PubMed
  24. Neuroradiology. 1997 Nov;39(11):811-4 - PubMed
  25. Cancer Discov. 2013 Apr;3(4):458-69 - PubMed
  26. J Neurosurg. 1984 Oct;61(4):782-5 - PubMed
  27. Surg Neurol. 2001 Mar;55(3):163-8; discussion 168 - PubMed
  28. J Neurooncol. 2000;46(1):57-61 - PubMed
  29. AJNR Am J Neuroradiol. 2003 Feb;24(2):287-90 - PubMed
  30. Korean J Radiol. 2013 Mar-Apr;14 (2):343-9 - PubMed
  31. Am J Clin Dermatol. 2002;3(6):401-26 - PubMed
  32. Zentralbl Neurochir. 2004;65(3):146-53 - PubMed

Publication Types