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Camplain R, Meyer ML, Tanaka H, et al. Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study. Am J Hypertens. 2015;29(11):1268-1275doi: 10.1093/ajh/hpv189.
Camplain, R., Meyer, M. L., Tanaka, H., Palta, P., Agarwal, S. K., Aguilar, D., Butler, K. R., & Heiss, G. (2016). Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study. American journal of hypertension, 29(11), 1268-1275. https://doi.org/10.1093/ajh/hpv189
Camplain, Ricky, et al. "Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." American journal of hypertension vol. 29,11 (2016): 1268-1275. doi: https://doi.org/10.1093/ajh/hpv189
Camplain R, Meyer ML, Tanaka H, Palta P, Agarwal SK, Aguilar D, Butler KR, Heiss G. Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study. Am J Hypertens. 2016 Nov 01;29(11):1268-1275. doi: 10.1093/ajh/hpv189. Epub 2015 Dec 10. PMID: 26657706; PMCID: PMC5055735.
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Am J Hypertens. 2016 Nov 01;29(11):1268-1275. doi: 10.1093/ajh/hpv189. Epub 2015 Dec 10.

Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study.

American journal of hypertension

Ricky Camplain, Michelle L Meyer, Hirofumi Tanaka, Priya Palta, Sunil K Agarwal, David Aguilar, Kenneth R Butler, Gerardo Heiss

Affiliations

  1. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; [email protected].
  2. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
  3. University of Texas at Austin, Austin, Texas, USA;
  4. Johns Hopkins University, Baltimore, Maryland, USA;
  5. Baylor College of Medicine, Houston, Texas, USA;
  6. University of Mississippi Medical Center, Jackson, Mississippi, USA.

PMID: 26657706 PMCID: PMC5055735 DOI: 10.1093/ajh/hpv189

Abstract

BACKGROUND: Though smoking is strongly associated with peripheral vascular disease and arteriosclerosis, smoking's association with arterial stiffness has been inconsistent and mostly limited to a single arterial segment. We examined the relationship between smoking behaviors with arterial stiffness in multiple arterial segments among community dwelling older adults.

METHODS: The cross-sectional relationship between smoking behavior with carotid-femoral (cfPWV) and femoral-ankle pulse wave velocity (faPWV) was examined in 5,002 men and women, separately, of the Atherosclerosis Risk in Communities (ARIC) cohort study. Brachial-ankle PWV was also assessed and presented in Supplementary Material. Heckman selection models were used to control for selective attrition and death in the ARIC cohort.

RESULTS: In women, faPWV was lower in current smokers compared to never smokers (-66.0cm/s; 95% confidence interval (95% CI): -94.6, -37.4), and was 1.0cm/s lower (95% CI: -1.8, -0.2) for every additional year a woman smoked, after adjustment for confounders. Among women, cfPWV was not associated with smoking status or cigarette pack-years. Additionally, no associations of smoking status and cigarette pack-years with PWV were observed among men. Years since smoking cessation was not associated with PWV in either gender.

CONCLUSION: Both smoking status and cumulative smoking exposure were associated with lower peripheral arterial stiffness among women, but not among men. We did not observe an association between central arterial stiffness and smoking status in either gender. The profound and well-documented adverse effects of cigarette smoking on the vasculature may not include a sustained stiffening of the arteries measured at older age.

© American Journal of Hypertension, Ltd 2015. All rights reserved. For Permissions, please email: [email protected].

Keywords: arterial stiffness; arteriosclerosis; blood pressure; central and peripheral arterial stiffness; health behavior; hypertension; smoking; smoking cessation; subclinical cardiovascular disease.

References

  1. Am J Pathol. 2013 May;182(5):1552-62 - PubMed
  2. Curr Med Chem. 2007;14(17):1887-92 - PubMed
  3. Am J Pathol. 2013 May;182(5):1489-93 - PubMed
  4. Am J Cardiol. 2008 Aug 15;102(4):491-6 - PubMed
  5. JAMA. 1998 Jan 14;279(2):119-24 - PubMed
  6. Br J Cancer. 2012 Jul 24;107(3):406-7 - PubMed
  7. Hellenic J Cardiol. 2006 Sep-Oct;47(5):263-8 - PubMed
  8. Am J Epidemiol. 1989 Apr;129(4):687-702 - PubMed
  9. BMC Cardiovasc Disord. 2013 Dec 01;13:109 - PubMed
  10. Atherosclerosis. 2006 Jun;186(2):441-7 - PubMed
  11. Circulation. 1997 Jan 7;95(1):31-8 - PubMed
  12. Am J Hypertens. 2016 Jan;29(1):114-22 - PubMed
  13. Circulation. 1993 Nov;88(5 Pt 1):2149-55 - PubMed
  14. Am J Hypertens. 2016 Apr;29(4):470-5 - PubMed
  15. J Hypertens. 1997 Dec;15(12 Pt 2):1659-64 - PubMed
  16. J Hypertens Suppl. 1992 Aug;10 (6):S87-91 - PubMed
  17. PLoS One. 2014 Nov 17;9(11):e112563 - PubMed
  18. BMC Cardiovasc Disord. 2006 Jan 19;6:3 - PubMed
  19. Neth J Med. 2004 Jul-Aug;62(7):235-41 - PubMed
  20. Circulation. 1994 Jul;90(1):248-53 - PubMed
  21. Blood Press Monit. 2009 Apr;14(2):69-75 - PubMed
  22. Cardiovasc Res. 1987 Sep;21(9):678-87 - PubMed
  23. Hypertension. 2007 May;49(5):981-5 - PubMed
  24. Blood Press. 2005;14(2):80-5 - PubMed
  25. Am J Cardiol. 1997 Jun 1;79(11):1538-41 - PubMed
  26. Angiology. 2006 Oct-Nov;57(5):564-8 - PubMed
  27. Angiology. 2013 May;64(4):273-80 - PubMed
  28. Hypertension. 2001 Jan;37(1):6-11 - PubMed
  29. Blood Press. 2005;14(1):45-52 - PubMed
  30. Clin Physiol. 1997 Nov;17 (6):569-77 - PubMed
  31. J Hypertens. 2006 Apr;24(4):683-9 - PubMed
  32. Br J Clin Pharmacol. 2006 Jun;61(6):767-73 - PubMed
  33. Eur J Clin Invest. 2004 Dec;34(12):825-30 - PubMed
  34. JAMA. 2003 Jul 2;290(1):86-97 - PubMed
  35. Hypertens Res. 2010 May;33(5):398-410 - PubMed
  36. Am J Clin Nutr. 1982 Nov;36(5):936-42 - PubMed
  37. J Korean Med Sci. 2014 Jun;29(6):798-804 - PubMed
  38. J Am Coll Cardiol. 1993 Dec;22(7):1881-6 - PubMed

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