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Ai DL, Li BT, Peng XM, et al. Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report. Oncol Lett. 2015;11(1):798-800doi: 10.3892/ol.2015.3934.
Ai, D. L., Li, B. T., Peng, X. M., Zhang, L. Z., Wang, J. Y., Zhao, Y., Yang, B., Yu, Q., Liu, C. Z., Yang, N., Wang, H. M., & Zhou, L. (2016). Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report. Oncology letters, 11(1), 798-800. https://doi.org/10.3892/ol.2015.3934
Ai, Ding-Lun, et al. "Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report." Oncology letters vol. 11,1 (2016): 798-800. doi: https://doi.org/10.3892/ol.2015.3934
Ai DL, Li BT, Peng XM, Zhang LZ, Wang JY, Zhao Y, Yang B, Yu Q, Liu CZ, Yang N, Wang HM, Zhou L. Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report. Oncol Lett. 2016 Jan;11(1):798-800. doi: 10.3892/ol.2015.3934. Epub 2015 Nov 17. PMID: 26870287; PMCID: PMC4727072.
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Oncol Lett. 2016 Jan;11(1):798-800. doi: 10.3892/ol.2015.3934. Epub 2015 Nov 17.

Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report.

Oncology letters

Ding-Lun Ai, Bo-Tao Li, Xiao-Ming Peng, Lin-Zhi Zhang, Jing-Yan Wang, Yun Zhao, Bin Yang, Qiang Yu, Chun-Zi Liu, Ning Yang, Hua-Ming Wang, Lin Zhou

Affiliations

  1. Department of Interventional Radiology, Beijing 302nd Hospital, Beijing 100039, P.R. China.
  2. Department of Hematopoietic Stem Cell Transplantation, Affiliated Hospital to the Chinese Academy of Military Medical Sciences, Beijing 100071, P.R. China.
  3. Department of Clinical Laboratory, Beijing 302nd Hospital, Beijing 100039, P.R. China.

PMID: 26870287 PMCID: PMC4727072 DOI: 10.3892/ol.2015.3934

Abstract

Percutaneous ethanol injection is an important localized treatment method for patients presenting with hepatocellular carcinoma (HCC). Among the advantages of percutaneous ethanol injection are its minimal invasiveness, simplicity, low cost and low risk of complications. However, the increasing popularity of percutaneous ethanol injection has resulted in serious adverse effects attributed to individual variations. The present study describes the case of a patient who exhibited acquired amegakaryocytic thrombocytopenic purpura, caused by percutaneous ethanol injection treatment for HCC. This complication was promptly identified, and platelet transfusion and injection of recombinant human interleukin-11 resulted in a rapid recovery of the patient's platelet count. Attention should be given to this rare complication in patients administered percutaneous ethanol injection treatment for HCC.

Keywords: acquired amegakaryocytic thrombocytopenic purpura; complication; hepatocellular carcinoma; percutaneous ethanol injection

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