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Nishimura M, Yoshida S, Haramoto M, et al. Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure. J Tradit Complement Med. 2015;6(1):66-71doi: 10.1016/j.jtcme.2014.11.022.
Nishimura, M., Yoshida, S., Haramoto, M., Mizuno, H., Fukuda, T., Kagami-Katsuyama, H., Tanaka, A., Ohkawara, T., Sato, Y., & Nishihira, J. (2016). Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure. Journal of traditional and complementary medicine, 6(1), 66-71. https://doi.org/10.1016/j.jtcme.2014.11.022
Nishimura, Mie, et al. "Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure." Journal of traditional and complementary medicine vol. 6,1 (2016): 66-71. doi: https://doi.org/10.1016/j.jtcme.2014.11.022
Nishimura M, Yoshida S, Haramoto M, Mizuno H, Fukuda T, Kagami-Katsuyama H, Tanaka A, Ohkawara T, Sato Y, Nishihira J. Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure. J Tradit Complement Med. 2015 Jan 08;6(1):66-71. doi: 10.1016/j.jtcme.2014.11.022. eCollection 2016 Jan. PMID: 26870683; PMCID: PMC4738072.
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J Tradit Complement Med. 2015 Jan 08;6(1):66-71. doi: 10.1016/j.jtcme.2014.11.022. eCollection 2016 Jan.

Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure.

Journal of traditional and complementary medicine

Mie Nishimura, Shin-Ichi Yoshida, Masafumi Haramoto, Hidenori Mizuno, Tomohiko Fukuda, Hiroyo Kagami-Katsuyama, Aiko Tanaka, Tatsuya Ohkawara, Yuji Sato, Jun Nishihira

Affiliations

  1. Department of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido, Japan.
  2. Hokuren Agricultural Research Institute, Higashi-ku, Sapporo, Japan.
  3. Satake Co., Ltd., Higashihiroshima, Hiroshima, Japan.

PMID: 26870683 PMCID: PMC4738072 DOI: 10.1016/j.jtcme.2014.11.022

Abstract

Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter with beneficial effects including antihypertension and antistress properties. In this study, we examined the effects of GABA-enriched white rice (GABA rice) on blood pressure (BP) in 39 mildly hypertensive adults in a randomized, double-blind, placebo-controlled study. The participants were divided into a test group (n = 22) who consumed rice with 11.2 mg GABA/100 g of rice and a placebo group (n = 17) who consumed rice with 2.7 mg GABA/100 g of rice. For 8 weeks, the participants took 150 g of either the GABA rice or the placebo rice. Hematological examinations were performed on both groups at 0, 4, and 8 weeks after the start of rice consumption. Home BP was self-measured two times daily, morning and evening, from 1 weeks before to 2 weeks after the intervention. Although the hospital BP and evening BP measurements of the participants showed no significant change, consumption of the GABA rice improved the morning BP compared with the placebo rice after the 1(st) week and during the 6(th) and 8(th) weeks. These results showed the possibility that the GABA rice improves morning hypertension.

Keywords: gamma-aminobutyric acid; gamma-aminobutyric acid-enriched white rice; home blood pressure; morning blood pressure; white rice

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