Display options
Cite
McClure EM, Bose CL, Garces A, et al. Global network for women's and children's health research: a system for low-resource areas to determine probable causes of stillbirth, neonatal, and maternal death. Matern Health Neonatol Perinatol. 2015;1:11doi: 10.1186/s40748-015-0012-7.
McClure, E. M., Bose, C. L., Garces, A., Esamai, F., Goudar, S. S., Patel, A., Chomba, E., Pasha, O., Tshefu, A., Kodkany, B. S., Saleem, S., Carlo, W. A., Derman, R. J., Hibberd, P. L., Liechty, E. A., Hambidge, K. M., Krebs, N. F., Bauserman, M., Koso-Thomas, M., Moore, J., Wallace, D. D., Jobe, A. H., & Goldenberg, R. L. (2015). Global network for women's and children's health research: a system for low-resource areas to determine probable causes of stillbirth, neonatal, and maternal death. Maternal health, neonatology and perinatology, 111. https://doi.org/10.1186/s40748-015-0012-7
McClure, Elizabeth M, et al. "Global network for women's and children's health research: a system for low-resource areas to determine probable causes of stillbirth, neonatal, and maternal death." Maternal health, neonatology and perinatology vol. 1 (2015): 11. doi: https://doi.org/10.1186/s40748-015-0012-7
McClure EM, Bose CL, Garces A, Esamai F, Goudar SS, Patel A, Chomba E, Pasha O, Tshefu A, Kodkany BS, Saleem S, Carlo WA, Derman RJ, Hibberd PL, Liechty EA, Hambidge KM, Krebs NF, Bauserman M, Koso-Thomas M, Moore J, Wallace DD, Jobe AH, Goldenberg RL. Global network for women's and children's health research: a system for low-resource areas to determine probable causes of stillbirth, neonatal, and maternal death. Matern Health Neonatol Perinatol. 2015 May 04;1:11. doi: 10.1186/s40748-015-0012-7. eCollection 2015. PMID: 27057328; PMCID: PMC4823684.
Copy Download .nbib Format: NLM
Share it on

Matern Health Neonatol Perinatol. 2015 May 04;1:11. doi: 10.1186/s40748-015-0012-7. eCollection 2015.

Global network for women's and children's health research: a system for low-resource areas to determine probable causes of stillbirth, neonatal, and maternal death.

Maternal health, neonatology and perinatology

Elizabeth M McClure, Carl L Bose, Ana Garces, Fabian Esamai, Shivaprasad S Goudar, Archana Patel, Elwyn Chomba, Omrana Pasha, Antoinette Tshefu, Bhalchandra S Kodkany, Sarah Saleem, Waldemar A Carlo, Richard J Derman, Patricia L Hibberd, Edward A Liechty, K Michael Hambidge, Nancy F Krebs, Melissa Bauserman, Marion Koso-Thomas, Janet Moore, Dennis D Wallace, Alan H Jobe, Robert L Goldenberg

Affiliations

  1. RTI International, Durham, NC USA.
  2. University of North Carolina at Chapel Hill, Chapel Hill, NC USA.
  3. FANCAP, Guatemala City, Guatemala.
  4. Moi University Medical Teaching Hospital, Eldoret, Kenya.
  5. KLE University's JN Medical College, Belgaum, India.
  6. Latta Medical Research Foundation, Indira Gandhi Medical School, Nagpur, India.
  7. University of Zambia, Lusaka, Zambia.
  8. Aga Khan University, Karachi, Pakistan.
  9. Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
  10. University of Alabama at Birmingham, Birmingham, AL USA.
  11. Christiana Health Care, Newark, DE USA.
  12. Massachusetts General Hospital, Boston, MA USA.
  13. Indiana University, Indianapolis, IN USA.
  14. University of Colorado, Denver, CO USA.
  15. UNC Chapel Hill, Chapel Hill, NC USA.
  16. Perinatology and Pregnancy Branch, NICHD, Bethesda, MD USA.
  17. Cincinnati Children's Hospital, Cincinnati, OH USA.
  18. Columbia University Medical Center, New York, NY USA.

PMID: 27057328 PMCID: PMC4823684 DOI: 10.1186/s40748-015-0012-7

Abstract

BACKGROUND: Determining cause of death is needed to develop strategies to reduce maternal death, stillbirth, and newborn death, especially for low-resource settings where 98% of deaths occur. Most existing classification systems are designed for high income settings where extensive testing is available. Verbal autopsy or audits, developed as an alternative, are time-intensive and not generally feasible for population-based evaluation. Furthermore, because most classification is user-dependent, reliability of classification varies over time and across settings. Thus, we sought to develop classification systems for maternal, fetal and newborn mortality based on minimal data to produce reliable cause-of-death estimates for low-resource settings.

RESULTS: In six low-resource countries (India, Pakistan, Guatemala, DRC, Zambia and Kenya), we evaluated data which are collected routinely at antenatal care and delivery and could be obtained with interview, observation, or basic equipment from the mother, lay-health provider or family to inform causes of death. Using these basic data collected in a standard way, we then developed an algorithm to assign cause of death that could be computer-programmed. Causes of death for maternal (trauma, abortion, hemorrhage, infection and hypertensive disease of pregnancy), stillbirth (birth trauma, congenital anomaly, infection, asphyxia, complications of preterm birth) and neonatal death (congenital anomaly, infection, asphyxia, complications of preterm birth) are based on existing cause of death classifications, and compatible with the World Health Organization International Classification of Disease system.

CONCLUSIONS: Our system to assign cause of maternal, fetal and neonatal death uses basic data from family or lay-health providers to assign cause of death by an algorithm to eliminate a source of inconsistency and bias. The major strengths are consistency, transparency, and comparability across time or regions with minimal burden on the healthcare system. This system will be an important contribution to determining cause of death in low-resource settings.

Keywords: Cause of death classification; Low-income Countries; Maternal mortality; Neonatal mortality; Stillbirth

References

  1. Lancet. 2014 Sep 13;384(9947):980-1004 - PubMed
  2. Bull World Health Organ. 2014 Aug 1;92(8):605-12 - PubMed
  3. J Paediatr Child Health. 2004 Jul;40(7):340-7 - PubMed
  4. Reprod Health. 2014 Feb 26;11(1):17 - PubMed
  5. Am J Forensic Med Pathol. 2006 Mar;27(1):11-9 - PubMed
  6. Trop Med Int Health. 2011 Jan;16(1):18-29 - PubMed
  7. Paediatr Perinat Epidemiol. 2008 Sep;22(5):417-29 - PubMed
  8. BMC Pregnancy Childbirth. 2009 Jun 10;9:22 - PubMed
  9. BMC Pregnancy Childbirth. 2010 Feb 23;10 Suppl 1:S1 - PubMed
  10. BMC Pregnancy Childbirth. 2009 Dec 17;9:58 - PubMed
  11. Placenta. 2008 Jan;29(1):71-80 - PubMed
  12. Eur J Obstet Gynecol Reprod Biol. 2009 Jun;144(2):99-104 - PubMed
  13. Bull World Health Organ. 2006 Sep;84(9):706-13 - PubMed
  14. Obstet Gynecol. 2010 Aug;116(2 Pt 1):254-60 - PubMed
  15. Paediatr Perinat Epidemiol. 2008 Sep;22(5):410-6 - PubMed
  16. Acta Obstet Gynecol Scand. 2008;87(11):1202-12 - PubMed
  17. Lancet Glob Health. 2014 Jun;2(6):e323-33 - PubMed
  18. Aust N Z J Obstet Gynaecol. 2012 Feb;52(1):62-6 - PubMed
  19. Aust N Z J Obstet Gynaecol. 2009 Oct;49(5):472-7 - PubMed
  20. BMJ. 2005 Nov 12;331(7525):1113-7 - PubMed
  21. Reprod Health. 2013;10 Suppl 1:S2 - PubMed
  22. Br J Obstet Gynaecol. 1997 Sep;104(9):1043-9 - PubMed
  23. Obstet Gynecol. 2007 Oct;110(4):963-6 - PubMed
  24. Trop Med Int Health. 2006 May;11(5):681-96 - PubMed
  25. Paediatr Perinat Epidemiol. 2008 Sep;22(5):430-7 - PubMed
  26. Acta Obstet Gynecol Scand. 2011 Dec;90(12):1379-85 - PubMed
  27. Int J Gynaecol Obstet. 2009 Oct;107 Suppl 1:S5-18, S19 - PubMed
  28. Aust N Z J Public Health. 2007 Oct;31(5):444-9 - PubMed
  29. BMC Pregnancy Childbirth. 2013 Oct 03;13:182 - PubMed
  30. Am J Obstet Gynecol. 2012 Jan;206(1):53.e1-53.e12 - PubMed
  31. J Nepal Health Res Counc. 2011 Oct;9(2):150-3 - PubMed
  32. BMC Pregnancy Childbirth. 2012 May 14;12:34 - PubMed
  33. Lancet. 2007 Nov 10;370(9599):1653-63 - PubMed
  34. Obstet Gynecol. 2014 Feb;123(2 Pt 1):325-36 - PubMed
  35. J Perinatol. 2012 Aug;32(8):585-92 - PubMed
  36. BMC Pregnancy Childbirth. 2009 Jun 19;9:24 - PubMed
  37. Glob Health Action. 2012 Sep 03;5:1-8 - PubMed
  38. Obstet Gynecol. 2009 Oct;114(4):901-14 - PubMed
  39. J Matern Fetal Neonatal Med. 2009 Mar;22(3):183-90 - PubMed
  40. Lancet. 2011 Sep 24;378(9797):1139-65 - PubMed
  41. Int J Gynaecol Obstet. 2012 Sep;118(3):190-3 - PubMed
  42. BMC Pediatr. 2014 Apr 22;14:108 - PubMed
  43. Int J Gynaecol Obstet. 2014 Jun;125(3):223-7 - PubMed
  44. Lancet. 2011 May 14;377(9778):1703-17 - PubMed
  45. Int J Gynaecol Obstet. 2013 Dec;123(3):252-3 - PubMed

Publication Types

Grant support