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Shoda K, Ikoma H, Yamamoto Y, et al. A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma. Surg Case Rep. 2015;1(1):30doi: 10.1186/s40792-015-0015-7.
Shoda, K., Ikoma, H., Yamamoto, Y., Kinoshita, O., Morimura, R., Konishi, H., Murayama, Y., Komatsu, S., Shiozaki, A., Kuriu, Y., Nakanishi, M., Ichikawa, D., Fujiwara, H., Okamoto, K., Sakakura, C., Ochiai, T., Taniguchi, H., Yasukawa, S., & Otsuji, E. (2015). A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma. Surgical case reports, 1(1), 30. https://doi.org/10.1186/s40792-015-0015-7
Shoda, Katsutoshi, et al. "A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma." Surgical case reports vol. 1,1 (2015): 30. doi: https://doi.org/10.1186/s40792-015-0015-7
Shoda K, Ikoma H, Yamamoto Y, Kinoshita O, Morimura R, Konishi H, Murayama Y, Komatsu S, Shiozaki A, Kuriu Y, Nakanishi M, Ichikawa D, Fujiwara H, Okamoto K, Sakakura C, Ochiai T, Taniguchi H, Yasukawa S, Otsuji E. A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma. Surg Case Rep. 2015 Dec;1(1):30. doi: 10.1186/s40792-015-0015-7. Epub 2015 Mar 18. PMID: 26943398; PMCID: PMC4747964.
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Surg Case Rep. 2015 Dec;1(1):30. doi: 10.1186/s40792-015-0015-7. Epub 2015 Mar 18.

A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma.

Surgical case reports

Katsutoshi Shoda, Hisashi Ikoma, Yusuke Yamamoto, Osamu Kinoshita, Ryo Morimura, Hirotaka Konishi, Yasutoshi Murayama, Shuhei Komatsu, Atsushi Shiozaki, Yoshiaki Kuriu, Masayoshi Nakanishi, Daisuke Ichikawa, Hitoshi Fujiwara, Kazuma Okamoto, Chohei Sakakura, Toshiya Ochiai, Hiroki Taniguchi, Satoshi Yasukawa, Eigo Otsuji

Affiliations

  1. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  2. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  3. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  4. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  5. Department of Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan. [email protected].
  6. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  7. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  8. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  9. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  10. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  11. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  12. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  13. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  14. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  15. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  16. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].
  17. Department of Surgery, North Medical Center Kyoto Prefectural University of Medicine, Kyoto, Japan. [email protected].
  18. Department of Surgery, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan. [email protected].
  19. Department of Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan. [email protected].
  20. Department of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan. [email protected].

PMID: 26943398 PMCID: PMC4747964 DOI: 10.1186/s40792-015-0015-7

Abstract

BACKGROUND: Merkel cell carcinoma (MCC) is a rare endocrine tumor that presents as a rapidly growing skin nodule of the body, and it is aggressive with regional nodal and distant metastases without clearly defined treatment. There are no reports of long survivors among patients with liver metastasis of MCC. The current case was a patient who underwent surgical resection for liver metastasis of Merkel cell carcinoma.

CASE PRESENTATION: This case describes a 73-year-old female with a papule on the dorsal side of the right third finger and liver tumor. The papule of the right third finger was histologically diagnosed as MCC by the skin biopsy. She underwent extensive resection and lymph node dissection of the right third finger and partial resection of the liver. The liver tumor was histologically diagnosed as liver metastasis of MCC. The patient remains well without any evidence of tumor recurrence more than 5 years after surgery.

CONCLUSIONS: This is the first report of a long-term survival of more than 5 years following liver metastasis of MCC, which was surgically resected. Patients with small and solitary metastatic liver tumor of MCC may have a chance for a long-term survival following the hepatic resection.

Keywords: Hepatectomy; Liver metastasis; Merkel cell carcinoma

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