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Showing 1 to 12 of 229 entries
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Pancreatic DCLK1 marks quiescent but oncogenic progenitors: a possible link to neuroendocrine tumors.

Stem cell investigation

Koga H, Ikezono Y, Torimura T.
PMID: 27668244
Stem Cell Investig. 2016 Aug 12;3:37. doi: 10.21037/sci.2016.08.03. eCollection 2016.

No abstract available.

A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma.

Surgical case reports

Shoda K, Ikoma H, Yamamoto Y, Kinoshita O, Morimura R, Konishi H, Murayama Y, Komatsu S, Shiozaki A, Kuriu Y, Nakanishi M, Ichikawa D, Fujiwara H, Okamoto K, Sakakura C, Ochiai T, Taniguchi H, Yasukawa S, Otsuji E.
PMID: 26943398
Surg Case Rep. 2015 Dec;1(1):30. doi: 10.1186/s40792-015-0015-7. Epub 2015 Mar 18.

BACKGROUND: Merkel cell carcinoma (MCC) is a rare endocrine tumor that presents as a rapidly growing skin nodule of the body, and it is aggressive with regional nodal and distant metastases without clearly defined treatment. There are no reports...

Adiponectin suppresses endoplasmic reticulum stress in nonalcoholic steatohepatitis.

Experimental and therapeutic medicine

Ueno T, Nakamura A, Nakayama H, Otabe S, Yuan X, Fukutani T, Iwamoto H, Nakamura T, Koga H, Torimura T, Sata M, Yamada K.
PMID: 22977616
Exp Ther Med. 2011 Nov;2(6):1035-1040. doi: 10.3892/etm.2011.348. Epub 2011 Sep 02.

In this study, we examined whether adiponectin suppresses endoplasmic reticulum (ER) stress in nonalcoholic steatohepatitis (NASH) using male transgenic mice expressing nSREBP-1c in adipose tissue, nSREBP-1c/adiponectin double-transgenic mice expressing human adiponectin in the liver, and wild-type male mice as...

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors.

Science advances

Iwamoto H, Zhang Y, Seki T, Yang Y, Nakamura M, Wang J, Yang X, Torimura T, Cao Y.
PMID: 26601163
Sci Adv. 2015 Apr 10;1(3):e1400244. doi: 10.1126/sciadv.1400244. eCollection 2015 Apr.

Inhibition of Dll4 (delta-like ligand 4)-Notch signaling-mediated tumor angiogenesis is an attractive approach in cancer therapy. However, inhibition of Dll4-Notch signaling has produced different effects in various tumors, and no biomarkers are available for predicting the anti-Dll4-Notch-associated antitumor activity....

Expression of nephronectin is enhanced by 1α,25-dihydroxyvitamin D3.

FEBS open bio

Hiranuma K, Yamada A, Kurosawa T, Aizawa R, Suzuki D, Saito Y, Nagahama R, Ikehata M, Tsukasaki M, Morimura N, Chikazu D, Maki K, Shirota T, Takami M, Yamamoto M, Iijima T, Kamijo R.
PMID: 27642554
FEBS Open Bio. 2016 Jul 13;6(9):914-8. doi: 10.1002/2211-5463.12085. eCollection 2016 Sep.

The extracellular matrix protein nephronectin (Npnt), also called POEM, is considered to play critical roles as an adhesion molecule in development and functions of various tissues, such as the kidneys, liver, and bone. In the present study, we examined...

Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathways.

FEBS open bio

Kurosawa T, Yamada A, Takami M, Suzuki D, Saito Y, Hiranuma K, Enomoto T, Morimura N, Yamamoto M, Iijima T, Shirota T, Itabe H, Kamijo R.
PMID: 25905035
FEBS Open Bio. 2015 Apr 08;5:303-7. doi: 10.1016/j.fob.2015.04.001. eCollection 2015.

Nephronectin (Npnt), also called POEM, is an extracellular matrix protein considered to play critical roles as an adhesion molecule in the development and functions of various tissues, such as the kidneys, liver, and bones. In the present study, we...

Indication of metronomic chemotherapy for metastatic breast cancer: Clinical outcomes and responsive subtypes.

Molecular and clinical oncology

Kontani K, Hashimoto SI, Murazawa C, Norimura S, Tanaka H, Ohtani M, Fujiwara-Honjo N, Date M, Teramoto K, Houchi H, Yokomise H.
PMID: 27284428
Mol Clin Oncol. 2016 Jun;4(6):947-953. doi: 10.3892/mco.2016.841. Epub 2016 Mar 30.

The survival of patients with metastatic breast cancer (MBC) has not improved, despite recent advances in therapeutic strategies. This is mainly due to the fact that cytotoxic agents cannot be administered over a long period, even if they exhibit...

Phenotype analysis of lymphoid cells in Marek's disease of CD4(+) or CD8(+) T-cell-deficient chickens: Occurrence of double negative T-cell tumour.

Avian pathology : journal of the W.V.P.A

Okada K, Tanaka Y, Murakami K, Chiba S, Morimura T, Hattori M, Goryo M, Onuma M.
PMID: 18483926
Avian Pathol. 1997;26(3):525-34. doi: 10.1080/03079459708419232.

Chickens rendered either CD4(+) or CD8(+) T-cell-deficient by thymectomy and subsequent inoculation of anti-CD4 or anti-CD8 monoclonal antibody (mAb), were infected with Marek's disease herpesvirus (MDV). All the non-treated control (4/4) and CD8-deficient chickens (5/5) formed gross tumours. However,...

Spin-flip transition of L1(0)-type MnPt alloy single crystal studied by neutron scattering.

Journal of physics. Condensed matter : an Institute of Physics journal

Hama H, Motomura R, Shinozaki T, Tsunoda Y.
PMID: 21690973
J Phys Condens Matter. 2007 Apr 30;19(17):176228. doi: 10.1088/0953-8984/19/17/176228. Epub 2007 Apr 16.

Magnetic structure, tetragonality, and the spin-flip transition for an L1(0)-type MnPt ordered alloy were studied by neutron scattering using a single-crystal specimen. Tetragonality of the lattice showed strong correlation with the spin-flip transition. Although the spin-flip transition looks like...

STEM image simulation by Bloch-wave method with layer-by-layer representation.

Journal of electron microscopy

Morimura T.
PMID: 20573745
J Electron Microsc (Tokyo). 2010 Aug;59:S23-8. doi: 10.1093/jmicro/dfq028. Epub 2010 Jun 23.

In a Bloch-wave-based STEM image simulation, a framework for calculating the cross section for any incoherent scattering process was formulated by Allen et al. [(2003) Lattice-resolution contrast from a focused coherent electron probe. Part I. Ultramicroscopy 96: 47-63; Part...

Serum albumin level is a notable profiling factor for non-B, non-C hepatitis virus-related hepatocellular carcinoma: A data-mining analysis.

Hepatology research : the official journal of the Japan Society of Hepatology

Yamada S, Kawaguchi A, Kawaguchi T, Fukushima N, Kuromatsu R, Sumie S, Takata A, Nakano M, Satani M, Tonan T, Fujimoto K, Shima H, Kakuma T, Torimura T, Charlton MR, Sata M.
PMID: 23819517
Hepatol Res. 2014 Aug;44(8):837-45. doi: 10.1111/hepr.12192. Epub 2013 Aug 04.

AIM: Various factors are underlying for the onset of non-B, non-C hepatitis virus-related hepatocellular carcinoma (NBNC-HCC). We aimed to investigate the independent risk factors and profiles associated with NBNC-HCC using a data-mining technique.METHODS: We conducted a case-control study and...

Evaluation of the effect of a chicken comb extract-containing supplement on cartilage and bone metabolism in athletes.

Experimental and therapeutic medicine

Yoshimura M, Aoba Y, Watari T, Momomura R, Watanabe K, Tomonaga A, Matsunaga M, Suda Y, Lee WY, Asai K, Yoshimura K, Nakagawa T, Yamamoto T, Yamaguchi H, Nagaoka I.
PMID: 23170108
Exp Ther Med. 2012 Oct;4(4):577-580. doi: 10.3892/etm.2012.646. Epub 2012 Jul 24.

In a previous study, we revealed that a commercially available product of dietary supplement containing a chicken comb extract (CCE), which is rich in hyaluronan, not only relieves joint pain and other symptoms, but also potentially improves the balance...

Showing 1 to 12 of 229 entries