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Therapie. 2006 Jan-Feb;61(1):17-22. doi: 10.2515/therapie:2006006.

[Not Available].

Therapie

[Article in French]
Hélène Verdoux, Marie Tournier, Audrey Cougnard, Karin Martin, Bernard Bégaud

Affiliations

  1. Université Victor Segalen Bordeaux 2, Bordeaux, France; INSERM U 657, IFR99 de Santé Publique, Bordeaux, France. Electronic address: [email protected].
  2. Université Victor Segalen Bordeaux 2, Bordeaux, France; INSERM U 657, IFR99 de Santé Publique, Bordeaux, France.
  3. INSERM U 657, IFR99 de Santé Publique, Bordeaux, France.

PMID: 27393128 DOI: 10.2515/therapie:2006006

Abstract

Pharmacoepidemiological studies exploring utilisation of psychotropic medications in real-life conditions are required to identify extension of indications, since the risk of gap between the theoretical target population and the population actually treated is especially marked for this class of drugs. A large proportion of subjects from the general population are exposed to psychotropic medications, so even a small increase in the risk of adverse effect may have major deleterious consequences for the health of the general population. Hence, pharmacoepidemiological studies are also required to explore the risk/benefit ratio of these drugs in real-life conditions. These studies may provide answers to currently unsolved public health questions, such as the long-term cognitive impact of exposure to benzodiazepines, the impact of antidepressant on suicidal behaviour, or the risks associated with enlarged use of antipsychotics. Only findings obtained by such studies may allow risk management and elaboration of guidelines based upon factual data.

Copyright © 2006 Société Française de Pharmacologie et de Thérapeutique. Publié par Elsevier Masson SAS.

Keywords: impact; impact studies; pharmacoepidemiology; pharmacoépidémiologie; psychotropes; psychotropic drugs; utilisation; utilisation studies

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