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Boisen J, Malone CH, Kelly B, et al. Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage. Case Rep Dermatol Med. 2016;2016:9067428doi: 10.1155/2016/9067428.
Boisen, J., Malone, C. H., Kelly, B., & Wagner, R. F. (2016). Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage. Case reports in dermatological medicine, 20169067428. https://doi.org/10.1155/2016/9067428
Boisen, Julie, et al. "Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage." Case reports in dermatological medicine vol. 2016 (2016): 9067428. doi: https://doi.org/10.1155/2016/9067428
Boisen J, Malone CH, Kelly B, Wagner RF. Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage. Case Rep Dermatol Med. 2016;2016:9067428. doi: 10.1155/2016/9067428. Epub 2016 May 16. PMID: 27293916; PMCID: PMC4884829.
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Case Rep Dermatol Med. 2016;2016:9067428. doi: 10.1155/2016/9067428. Epub 2016 May 16.

Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage.

Case reports in dermatological medicine

Julie Boisen, C Helen Malone, Brent Kelly, Richard F Wagner

Affiliations

  1. Department of Dermatology, University of Texas Medical Branch, Galveston, TX 77550, USA.

PMID: 27293916 PMCID: PMC4884829 DOI: 10.1155/2016/9067428

Abstract

Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin.

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