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J Clin Biochem Nutr. 2016 Sep;59(2):134-138. doi: 10.3164/jcbn.15-147. Epub 2016 Jun 10.

Effects of isoflavones on lipid and apolipoprotein levels in patients with type 2 diabetes in Heilongjiang Province in China.

Journal of clinical biochemistry and nutrition

Xiao-Xing Chi, Tao Zhang, Dong-Jie Zhang, Wei Yu, Qiu-Ying Wang, Jing-Long Zhen

Affiliations

  1. Department of Food College, School of Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, China.
  2. Department of Inspection, Harbin Medical University-Daqing, Daqing, Heilongjiang Province, China.
  3. National Coarse Cereals Engineering Research Center, Daqing, Heilongjiang Province, China.
  4. Daqing Hospital of Traditional Chinese Medicine, Daqing, Heilongjiang Province, China.

PMID: 27698541 PMCID: PMC5018568 DOI: 10.3164/jcbn.15-147

Abstract

In this study, we examined the association between soy isoflavones and lipid profiles, apolipoprotein levels in patients with type 2 diabetes in China. The study population was composed of 120 cases (80 women with type 2 diabetes and 40 healthy women). Objects in treatment group received isoflavones 435 mg/day for 2 months, then lipid profiles were analyzed by the colorimetry method and apolipoprotein levels were determined by immune turbidimetric method. And all the indexes were determined after oral glucose tolerance test. The levels of total cholesterol, triglyceride and LDL-C significantly reduced and the levels of HDL-C and apolipoprotein A1 significantly raised in the treatment group after intervention (

Keywords: China; apolipoprotein; isoflavones; lipid profiles; type 2 diabetes

Conflict of interest statement

No potential conflicts of interest were disclosed.

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