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SSM Popul Health. 2016 Dec;2:416-424. doi: 10.1016/j.ssmph.2016.05.003. Epub 2016 May 09.

Nativity differences in allostatic load by age, sex, and Hispanic background from the Hispanic Community Health Study/Study of Latinos.

SSM - population health

Christian R Salazar, Garrett Strizich, Teresa E Seeman, Carmen R Isasi, Linda C Gallo, M Larissa Avilés-Santa, Jianwen Cai, Frank J Penedo, Willian Arguelles, Anne E Sanders, Richard B Lipton, Robert C Kaplan

Affiliations

  1. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx N Y.
  2. Departments of Epidemiology and Medicine, University of California, Los Angeles.
  3. Department of Psychology, San Diego State University, San Diego, CA.
  4. National Heart, Lung, and Blood Institute at the National Institutes of Health.
  5. University of North Carolina Gillings School of Global Public Health, Department of Biostatistics, Chapel Hill, NC.
  6. Department of Medical Social Sciences, Northwestern University, Chicago, IL.
  7. Department of Psychology, University of Miami, Miami, FL.
  8. Department of Dental Ecology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
  9. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx N Y; Departments of Neurology, Psychiatry, and Behavioral Sciences, Albert Einstein College of Medicine, Bronx NY.

PMID: 27540567 PMCID: PMC4985030 DOI: 10.1016/j.ssmph.2016.05.003

Abstract

Allostatic load (AL), an index of biological "wear and tear" on the body from cumulative exposure to stress, has been little studied in US Hispanics/Latinos. We investigated AL accumulation patterns by age, sex, and nativity in the Hispanic Community Health Study/Study of Latinos. We studied 15,830 Hispanic/Latinos of Mexican, Cuban, Dominican, Puerto Rican, Central and South American descent aged 18-74 years, 77% of whom were foreign-born. Consistent with the conceptualization of AL, we developed an index based upon 16 physiological markers that spanned the cardiometabolic, parasympathetic, and inflammatory systems. We computed mean adjusted AL scores using log-linear models across age-groups (18-44, 45-54, 55-74 years), by sex and nativity status. Among foreign-born individuals, differences in AL by duration of residence in the US (<10, ≥10 years) and age at migration (<24, ≥24 years) were also examined. In persons younger than 55 years old, after controlling for socioeconomic and behavioral factors, AL was highest among US-born individuals, intermediate in foreign-born Hispanics/Latinos with longer duration in the US (≥10 years), and lowest among those with shorter duration in the US (<10 years) (

Keywords: Allostatic load; Hispanic ethnicity; age patterns; nativity; physiological dysregulation

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