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Urso K, Alvarez D, Cremasco V, et al. IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease. JCI Insight. 2016;1(12)doi: 10.1172/jci.insight.88057.
Urso, K., Alvarez, D., Cremasco, V., Tsang, K., Grauel, A., Lafyatis, R., von Andrian, U. H., Ermann, J., & Aliprantis, A. O. (2016). IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease. JCI insight, 1(12), . https://doi.org/10.1172/jci.insight.88057
Urso, Katia, et al. "IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease." JCI insight vol. 1,12 (2016). doi: https://doi.org/10.1172/jci.insight.88057
Urso K, Alvarez D, Cremasco V, Tsang K, Grauel A, Lafyatis R, von Andrian UH, Ermann J, Aliprantis AO. IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease. JCI Insight. 2016 Aug 04;1(12). doi: 10.1172/jci.insight.88057. PMID: 27547823; PMCID: PMC4988402.
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JCI Insight. 2016 Aug 04;1(12). doi: 10.1172/jci.insight.88057.

IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease.

JCI insight

Katia Urso, David Alvarez, Viviana Cremasco, Kelly Tsang, Angelo Grauel, Robert Lafyatis, Ulrich H von Andrian, Joerg Ermann, Antonios O Aliprantis

Affiliations

  1. Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  2. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
  3. Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  4. Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
  5. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA; Ragon Institute of Massachusetts General Hospital (MGH), MIT, and Harvard, Cambridge, Massachusetts, USA.

PMID: 27547823 PMCID: PMC4988402 DOI: 10.1172/jci.insight.88057

Abstract

Systemic sclerosis (SSc) is a potentially fatal autoimmune disorder with limited therapeutic options. Sclerodermatous graft versus host disease (sclGvHD), induced by transfer of B10.D2 splenocytes into BALB/c

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