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Barrett T, Haider MA. The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges. AJR Am J Roentgenol. 2016;208(1):131-139doi: 10.2214/AJR.16.16355.
Barrett, T., & Haider, M. A. (2017). The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges. AJR. American journal of roentgenology, 208(1), 131-139. https://doi.org/10.2214/AJR.16.16355
Barrett, Tristan, and Haider, Masoom A. "The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges." AJR. American journal of roentgenology vol. 208,1 (2017): 131-139. doi: https://doi.org/10.2214/AJR.16.16355
Barrett T, Haider MA. The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges. AJR Am J Roentgenol. 2017 Jan;208(1):131-139. doi: 10.2214/AJR.16.16355. Epub 2016 Oct 11. PMID: 27726415.
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AJR Am J Roentgenol. 2017 Jan;208(1):131-139. doi: 10.2214/AJR.16.16355. Epub 2016 Oct 11.

The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges.

AJR. American journal of roentgenology

Tristan Barrett, Masoom A Haider

Affiliations

  1. 1 Department of Radiology, Addenbrooke's Hospital and the University of Cambridge, Hills Rd, Cambridge, CB2 0QQ, UK.
  2. 2 Department of Medical Imaging, Sunnybrook Health Sciences Center and University of Toronto, Toronto, ON, Canada.

PMID: 27726415 DOI: 10.2214/AJR.16.16355

Abstract

OBJECTIVE: Active surveillance (AS) has emerged as a management strategy for preventing overtreatment of indolent prostate cancer. Selection of patients for AS has traditionally proved challenging and resulted in 20-30% misclassification rates. MRI has potential to help overcome this limitation, broaden selection criteria to increase recruitment, and minimize the invasive nature of AS follow-up.

CONCLUSION: The main issues surrounding MRI and AS are the heterogeneity of inclusion criteria, the definition of significant disease, and agreement about what constitutes radiologic progression. Prospective cohorts with MRI at enrollment and long-term follow-up are required to further address these issues.

Keywords: active surveillance; multiparametric MRI; prostate cancer

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