Display options
Cite
Nazar CM, Bashir F, Izhar S, et al. Overview of management of acute renal failure and its evaluation; a case analysis. J Nephropharmacol. 2015;4(1):17-22
Nazar, C. M., Bashir, F., Izhar, S., & Anderson, J. (2015). Overview of management of acute renal failure and its evaluation; a case analysis. Journal of nephropharmacology, 4(1), 17-22.
Nazar, Chaudhary Muhammad Junaid, et al. "Overview of management of acute renal failure and its evaluation; a case analysis." Journal of nephropharmacology vol. 4,1 (2015): 17-22.
Nazar CM, Bashir F, Izhar S, Anderson J. Overview of management of acute renal failure and its evaluation; a case analysis. J Nephropharmacol. 2015 Jan 01;4(1):17-22. eCollection 2015. PMID: 28197469; PMCID: PMC5297473.
Copy Download .nbib Format: NLM
Share it on

J Nephropharmacol. 2015 Jan 01;4(1):17-22. eCollection 2015.

Overview of management of acute renal failure and its evaluation; a case analysis.

Journal of nephropharmacology

Chaudhary Muhammad Junaid Nazar, Faisal Bashir, Saba Izhar, John Anderson

Affiliations

  1. Department of Endocrinology, University of Buckingham, Royal Gwent Hospital, NHS Trust, Wales, UK.
  2. Department of ENT, New City Teaching Hospital, Mohetarma Benazir Bhutto Shaheed Medical College, Mirpur Azad Kashmir, Pakistan.
  3. Department of Internal Medicine, Allma Iqbal Memorial Teaching Hospital Sialkot, Punjab, Pakistan.
  4. Division of Medical Education, Postgraduate Medicine Brighton and Sussex Medical School University of Brighton, Brighton, UK.

PMID: 28197469 PMCID: PMC5297473

Abstract

The annual incidence is about 150 per million in the UK, but this figure is six times greater in the >80 years old group. Prerenal azotemia is considered as the most serious reason in community or hospital acquired acute renal failure (ARF). A 67-year-old middle age male was admitted to the hospital with a chief complaint of generalized weakness, volume depletion and dysuria. He has treated with metronidazole for diarrhoea caused by Clostridium difficile considered as the precipitating factor for the ARF. The patient has severe osteoarthritis and takes high dose non-steroidal anti-inflammatory drugs from the last two years. He also complains for obstructive sleep apnea (OSA) and obesity. He has controlled hypertension was on lisinopril to control blood pressure. ARF is quite common, occurring in 80 million populations. Urinary obstruction should be excluded (a cause in around 5-10 of cases) because this is readily reversible if it is diagnosed early. A renal US will be sufficient to identify obstruction in 95 of cases. Most cases of ARF are expected to pre renal failure/acute tubular necrosis (ATN) 70-80%. Risk factor for development for at ATN are old age, drugs (non-steroidal anti-inflammatory drugs, gentamicin), sepsis, and chronic kidney disease and must be considered.

Keywords: Acute tubular necrosis; Glomerular filtration rate; Hemodialysis

References

  1. Ann Intern Med. 2005 Apr 5;142(7):510-24 - PubMed
  2. Am J Hypertens. 1993 Jul;6(7 Pt 2):251S-259S - PubMed
  3. Nephrol Dial Transplant. 2004 Nov;19(11):2747-53 - PubMed
  4. Crit Care. 2007;11(2):R31 - PubMed
  5. Curr Opin Nephrol Hypertens. 2007 Nov;16(6):557-64 - PubMed
  6. Kidney Int. 2010 Jun;77(11):1020-30 - PubMed
  7. Kidney Int. 2004 Dec;66(6):2389-401 - PubMed
  8. Transplantation. 2000 Jul 15;70(1):122-6 - PubMed
  9. QJM. 2006 Apr;99(4):245-51 - PubMed
  10. Kidney Int. 1996 Sep;50(3):811-8 - PubMed
  11. N Engl J Med. 2001 Nov 8;345(19):1368-77 - PubMed
  12. Best Pract Res Clin Anaesthesiol. 2004 Mar;18(1):37-52 - PubMed
  13. Kidney Int. 2009 Aug;76(4):422-7 - PubMed
  14. Curr Pharm Des. 2005;11(14):1795-804 - PubMed
  15. Am J Kidney Dis. 2009 Jan;53(1 Suppl):S1-374 - PubMed

Publication Types