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Li Y, Zhu L, Fan Y, et al. Formation and Controlled Drug Release Using a Three-Component Supramolecular Hydrogel for Anti-. Nanomaterials (Basel). 2016;6(3)doi: 10.3390/nano6030046.
Li, Y., Zhu, L., Fan, Y., Li, Y., Cheng, L., Liu, W., Li, X., & Fan, X. (2016). Formation and Controlled Drug Release Using a Three-Component Supramolecular Hydrogel for Anti-. Nanomaterials (Basel, Switzerland), 6(3), . https://doi.org/10.3390/nano6030046
Li, Yibao, et al. "Formation and Controlled Drug Release Using a Three-Component Supramolecular Hydrogel for Anti-." Nanomaterials (Basel, Switzerland) vol. 6,3 (2016). doi: https://doi.org/10.3390/nano6030046
Li Y, Zhu L, Fan Y, Li Y, Cheng L, Liu W, Li X, Fan X. Formation and Controlled Drug Release Using a Three-Component Supramolecular Hydrogel for Anti-. Nanomaterials (Basel). 2016 Mar 09;6(3). doi: 10.3390/nano6030046. PMID: 28344302; PMCID: PMC5302511.
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Nanomaterials (Basel). 2016 Mar 09;6(3). doi: 10.3390/nano6030046.

Formation and Controlled Drug Release Using a Three-Component Supramolecular Hydrogel for Anti-.

Nanomaterials (Basel, Switzerland)

Yibao Li, Lei Zhu, Yulan Fan, Yayun Li, Linxiu Cheng, Wei Liu, Xun Li, Xiaolin Fan

Affiliations

  1. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  2. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  3. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  4. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  5. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  6. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  7. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].
  8. Key Laboratory of Organo-pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China. [email protected].

PMID: 28344302 PMCID: PMC5302511 DOI: 10.3390/nano6030046

Abstract

A novel three-component supramolecular hydrogel based on riboflavin, melamine and amino acid derivatives were constructed for controlled release of pesticides, Niclosamide derivatives. The formation of hydrogel may be attributed to self-assemble via hydrogen bonding and π-π interaction, which have been researched via scanning electron microscopy (SEM) and Fourier transform infrared (FT-IR) spectra. The rheological experiments showed that the hydrogel materials and drug-loaded hydrogel all demonstrated good mechanical strength and high stability. Further experimental results indicated that the drug-loaded hydrogels show large drug loadings, long-term release time and relatively higher efficiency to anti-cercariae in the water environment.

Keywords: anti-cercariae; drug release; hydrogel; long-term release time

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