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Int J Dent. 2017;2017:8465125. doi: 10.1155/2017/8465125. Epub 2017 Feb 28.

Genetic Association of .

International journal of dentistry

D D Lewis, J R Shaffer, E Feingold, M Cooper, M M Vanyukov, B S Maher, R L Slayton, M C Willing, S E Reis, D W McNeil, R J Crout, R J Weyant, S M Levy, A R Vieira, M L Marazita

Affiliations

  1. Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
  2. Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
  3. Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  4. Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  5. Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
  6. Department of Pediatric Dentistry, School of Dentistry, University of Washington, Seattle, WA, USA.
  7. Division of Genetics and Genomic Medicine, Department of Pediatrics, School of Medicine, Washington University at St. Louis, St. Louis, MO, USA.
  8. Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  9. Psychology, Dental Practice and Rural Health, West Virginia University, Morgantown, WV, USA.
  10. Department of Periodontics, School of Dentistry, West Virginia University, Morgantown, WV, USA.
  11. Department of Dental Public Health and Information Management, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  12. Department of Preventive and Community Dentistry, University of Iowa College of Dentistry, Iowa City, IA, USA; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA.
  13. Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

PMID: 28348596 PMCID: PMC5350286 DOI: 10.1155/2017/8465125

Abstract

Matrix metalloproteinases (MMPs), which degrade extracellular proteins as part of a variety of physiological processes, and their inhibitors have been implicated in the dental caries process. Here we investigated 28 genetic variants spanning the

Conflict of interest statement

The authors declare no conflict of interests.

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