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Pharmacol Res Perspect. 2017 Mar 10;5(2):e00301. doi: 10.1002/prp2.301. eCollection 2017 Apr.

Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice.

Pharmacology research & perspectives

Brian D Fink, Deng Fu Guo, Chaitanya A Kulkarni, Kamal Rahmouni, Robert J Kerns, William I Sivitz

Affiliations

  1. Department of Internal Medicine/Endocrinology University of Iowa and the Iowa City Veterans Affairs Medical Center Iowa City Iowa 52242.
  2. Department of Pharmacology University of Iowa Iowa City Iowa 52242.
  3. Department of Pharmaceutical Sciences and Experimental Therapeutics University of Iowa Iowa City Iowa 52242.
  4. Departments of Pharmacology and Internal Medicine University of Iowa Iowa City Iowa 52242.

PMID: 28357127 PMCID: PMC5368965 DOI: 10.1002/prp2.301

Abstract

We recently reported that mitoquinone (mitoQ, 500 

Keywords: Antioxidants; Obesity; coenzyme Q; leptin; mitochondria; neuropeptide Y

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